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1.
Fig. 1

Fig. 1. From: Cerebrospinal fluid volumetric MRI mapping as a simple measurement for evaluating brain atrophy.

A ) CSF M0 map; the signal in each voxel is scaled to pure ventricular voxels to estimate the partial volume effect from which the CSF volume can be calculated. B ) R2 (= the inverse of the T2) CSF map. C ) Regions of interest used to retrieve the peripheral subarachnoidal (red) and ventricular T2, CSF values

J. B. De Vis, et al. Eur Radiol. 2016;26:1254-1262.
2.
Fig. 3

Fig. 3. From: Cerebrospinal fluid volumetric MRI mapping as a simple measurement for evaluating brain atrophy.

Bland-Altman plot demonstrating the agreement between the low and high resolution CSF MRI sequence performed within the same session. The coefficient of repeatability for the relative CSF volumes (figure on the left, CSF volumes expressed as a percentage of intracranial volume), was 14. The coefficient of repeatability for the T2 within the total CSF was 9.5

J. B. De Vis, et al. Eur Radiol. 2016;26:1254-1262.
3.
Fig. 2

Fig. 2. From: Cerebrospinal fluid volumetric MRI mapping as a simple measurement for evaluating brain atrophy.

CSF MRI sequence chart, the sequence is built of three parts. (1) Part 1, a nonselective (NS) saturation pulse followed by a time delay. (2) Part two, a NS MLEV T2-preparation, based on a τCPMG of 70 ms and 0, 4, 8, and 16 refocusing pulses. From these, effective TEs of 0, 280, 560, and 1120 ms are created. (3) In between parts 2 and 3, an optional inversion pulse can be applied which can compensate for slice-timing differences in multi-slice readout. (4) Part three, a multi-slice single-shot echo planar imaging (EPI) readout

J. B. De Vis, et al. Eur Radiol. 2016;26:1254-1262.

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