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Items: 5

1.
Fig. 4

Fig. 4. From: Dexketoprofen/tramadol: randomised double-blind trial and confirmation of empirical theory of combination analgesics in acute pain.

Cumulative frequency (Kaplan-Meier estimation) of RM intake (0–24 h)

R. Andrew Moore, et al. J Headache Pain. 2015;16:60.
2.
Fig. 3

Fig. 3. From: Dexketoprofen/tramadol: randomised double-blind trial and confirmation of empirical theory of combination analgesics in acute pain.

Time course of mean PAR scores (0–24 h). PAR measured on a 5-point VRS (0 = ‘none’ to 4 = ‘complete’)

R. Andrew Moore, et al. J Headache Pain. 2015;16:60.
3.
Fig. 5

Fig. 5. From: Dexketoprofen/tramadol: randomised double-blind trial and confirmation of empirical theory of combination analgesics in acute pain.

PGE at the end of the assessment period. PGE measured on a 5-point VRS (1 = ‘poor’ to 5 = ‘excellent’)

R. Andrew Moore, et al. J Headache Pain. 2015;16:60.
4.
Fig. 1

Fig. 1. From: Dexketoprofen/tramadol: randomised double-blind trial and confirmation of empirical theory of combination analgesics in acute pain.

Percentage of patients showing response (≥50 % max TOTPAR) over 6 h post-dose (Primary Endpoint). Maximum TOTPAR corresponds to the theoretical maximum possible time-weighted sum of the PAR scores, measured on a 5-point VRS (0 = ‘none’ to 4 = ‘complete’)

R. Andrew Moore, et al. J Headache Pain. 2015;16:60.
5.
Fig. 2

Fig. 2. From: Dexketoprofen/tramadol: randomised double-blind trial and confirmation of empirical theory of combination analgesics in acute pain.

NNT for ≥ 50 % max TOTPAR compared with placebo over six hours post dose. Maximum TOTPAR corresponds to the theoretical maximum possible time-weighted sum of the PAR scores, measured on a 5-point VRS (0 = ‘none’ to 4 = ‘complete’). Bars show 95 % confidence interval of NNT, with colour change as point estimate (Note that TRAM37.5 was not significantly better than placebo)

R. Andrew Moore, et al. J Headache Pain. 2015;16:60.

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