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1.
Figure 1

Figure 1. From: Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD.

Daily dose of extrafine beclomethasone and larger-particle fluticasone as prescribed on the index date for (A) the initiation sample and (B) the step-up sample.
Notes: P<0.001 for the differences between cohorts. Percentages may not add up to 100% because of rounding; x-axis not to scale.
Abbreviations: BDP, beclomethasone dipropionate; FP, fluticasone propionate.

Dirkje S Postma, et al. Int J Chron Obstruct Pulmon Dis. 2014;9:1163-1186.

CitationFull text

2.
Figure 2

Figure 2. From: Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD.

Percentage of patients experiencing 0, 1, or ≥2 COPD exacerbations during the baseline year and years 1 and 2 of the 2 year outcome period in (A) the initiation sample and (B) the step-up sample.
Abbreviations: COPD, chronic obstructive pulmonary disease; BDP, beclomethasone dipropionate.

Dirkje S Postma, et al. Int J Chron Obstruct Pulmon Dis. 2014;9:1163-1186.

CitationFull text

3.

Figure 3. From: Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD.

Changes in treatment and ICS dose during the 2 year outcome period for the (A) extrafine beclomethasone initiation cohort, (B) fluticasone initiation cohort, (C) extrafine beclomethasone step-up cohort, (D) fluticasone step-up cohort.
Note: “Other” includes LTRA and theophylline.
Abbreviations: BDP, beclomethasone dipropionate; FDC, fixed-dose combination ICS-LABA; ICS, inhaled corticosteroid; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; LTRA, leukotriene receptor antagonist.

Dirkje S Postma, et al. Int J Chron Obstruct Pulmon Dis. 2014;9:1163-1186.

CitationFull text

4.
Figure 4

Figure 4. From: Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD.

Mean daily ICS dose exposure for extrafine beclomethasone and fluticasone cohorts during the 2 year outcome period by (A) the initiation sample and (B) the step-up sample.
Notes: P<0.001 for the differences between cohorts. Percentages may not add up to 100% because of rounding. The mean daily dose exposure for each patient was calculated as the number of days’ supply divided by 730.
Abbreviations: BDP, beclomethasone dipropionate; FP, fluticasone propionate; ICS, inhaled corticosteroid.

Dirkje S Postma, et al. Int J Chron Obstruct Pulmon Dis. 2014;9:1163-1186.

CitationFull text

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