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Fig. 4. In vivo effects of AR-42. From: Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.
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Fig. 2. A global deficiency of H3K4me3in the dentate gyrus associated with reduced granule cell layer volume and neurogenesis in Kmt2d+/βGeo mice. From: Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.
Fig. 3. H3K4me3 epigenetic reporter allele demonstrated decreased activity in Kmt2d+/βGeocells. From: Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.
Fig. 1. Hippocampal memory defects in a Kmt2d+/βGeo mouse model of Kabuki syndrome. From: Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.
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