PMC

Oligotype distribution among sample groups. Red dots below group names indicate samples collected from Brazil, and blue dots identify samples collected from the United States.

Example distribution patterns for (a) ‘cosmopolitan', (b) ‘host-preferred', (c) ‘host-associated' and (d) ‘host-specific' oligotypes. Bars show relative abundances of hypothetical oligotypes and are colored based on host species— X, Y and Z.

Dendrogram of Blautia oligotypes and their host occurrence patterns. Bars show the proportion of animal or human samples in which the given oligotype is present. Circles indicate host-associated oligotypes. Host-specific oligotypes are denoted with stars. Background colors for oligotypes alternate between green and gray, where green indicates that a perfect hit with 100% coverage is found for a given oligotype in NCBI's non redundant database.

Network analysis of samples with respect to Blautia oligotypes. Edges connect samples to oligotypes and are colored based on the sample. A force-directed algorithm is used to analyze the occurrence of oligotypes in samples to reach equilibrium. Force-directed algorithms mimic basic physical properties such as repulsion and gravity, through which samples that share similar oligotypes are drawn together, while samples that have different oligotype profiles are pushed away from each other.

Shared and distinct oligotypes in sewage and Brazilian human fecal samples. The Venn diagram shows the number of shared oligotypes between the three sewage samples. The bar plot shows the abundance of each oligotype found in sewage samples. The color of each bar corresponds to the regions of the same color in the Venn diagram. The lower panel is a heat map that uses presence (green) and absence (red) to show the distribution of each oligotype among 10 samples collected from Brazilian humans. Colors listed in the key below the heat map follow the colors given to corresponding bars and Venn diagram.