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1.
Figure 1

Figure 1. From: A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.

Flow diagram of the tumor sample selection and classification.

Junfeng Xia, et al. Mol Cancer Ther. ;13(7):1918-1928.

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2.
Figure 2

Figure 2. Location of the additional mutations detected in BRAF in the 69 pan-negative melanoma samples. From: A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.

RBD: Raf-like Ras-binding domain (amino acids 155–227); C1_1: phorbol esters/diacylglycerol binding domain (amino acids 235–282); Pkinase: kinase domain (amino acids 457–714). Protein domain information was obtained from the Pfam database (http://pfam.sanger.ac.uk) and was visualized using DOG software (http://dog.biocuckoo.org). Mutations are indicated in blue.

Junfeng Xia, et al. Mol Cancer Ther. ;13(7):1918-1928.

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