Combined associations of gestational age at birth, birth weight, and infant weight gain with preschool wheezing and school-age asthma. Values are ORs (95% CIs) from multilevel models for the associations of gestational age at birth and birth weight SDSs (A and B), gestational age at birth and infant weight gain (C and D), and birth weight SDSs and infant weight gain (E and F) with asthma outcomes. Models are adjusted for confounders (see the section). Reference groups are represented by a white bar. P values for gestational age*SD birth weight interactions are as follows: wheezing, .97; asthma, .04. P values for gestational age*weight gain interaction are as follows: wheezing, .05; asthma, .23. P values for birth weight SDS*weight gain interactions are as follows: wheezing, .15; asthma, .57. *P < .05, **P < .01, and ***P < .001.