PMC

Overall survival is illustrated for patients with (+) and without (−) v-raf murine sarcoma viral oncogene homolog B (BRAF) mutations. The Kaplan-Meier method was used to estimate overall survival. Curves are compared using the log-rank test.

Mutation frequency is illusrated by tumor site. An asterisk denotes statistical significance (P < .05). The percentage frequency is listed above each column. APC indicates adenomatosis polyposis coli; BRAF, v-raf murine sarcoma viral oncogene homolog B; KRAS, Kirsten rat sarcoma viral oncogene homolog; NRAS, neuroblastoma RAS viral oncogene homolog; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit α; TP53, tumor protein p53.