PMC

The flow chart shows the different steps of prediction and filtration with the number of individual SNVs, miRNAs, and pairs of these at each stage.

The networks represent the interaction between genes that were predicted to have SNVs' effect on UTRs from miRNA and RNAsnp analysis (see , column 5). The gene nodes were colored to differentiate the known (orange) and unknown (green) cancer-associated genes, and the color outside the node indicates whether the gene comes from miRNA (yellow) or RNAsnp (blue) or both.

The dot plot from RNAsnp web server shows the base pair probabilities corresponds to the local region predicted with significant difference (d_max p-value: 0.0474) between wild-type and mutant. The upper triangle represents the base pair probabilities for the wild-type (green) and the lower triangle for the mutant (red). On the sides, the minimum free energy (MFE) structure of the wild-type and mutants are displayed in planar graphic representation. The SECIS region is highlighted in blue circle and the SNV position is indicated with arrow mark.