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Figure 1. In vivo BBBD induced by FUS and monitored by 2PFM imaging. From: Drug Delivery to the Brain by Focused Ultrasound Induced Blood-Brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-Photon Microscopy.
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Figure 5. BBBD onset in relation to permeability and acoustic pressure. From: Drug Delivery to the Brain by Focused Ultrasound Induced Blood-Brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-Photon Microscopy.
Figure 6. Effect of vessel diameter on enhanced BBB permeability. From: Drug Delivery to the Brain by Focused Ultrasound Induced Blood-Brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-Photon Microscopy.
Figure 3. Effect of acoustic pressure on permeability dextran conjugated Texas Red across the BBB. From: Drug Delivery to the Brain by Focused Ultrasound Induced Blood-Brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-Photon Microscopy.
Figure 4. Effect of substance size on enhanced BBB permeability. From: Drug Delivery to the Brain by Focused Ultrasound Induced Blood-Brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-Photon Microscopy.
Figure 2. Data analysis of 2PFM data capturing fluorescent dye leakage upon BBBD. From: Drug Delivery to the Brain by Focused Ultrasound Induced Blood-Brain Barrier Disruption: Quantitative Evaluation of Enhanced Permeability of Cerebral Vasculature Using Two-Photon Microscopy.
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