PMC

Illustration of 1-back, 2-back, 3-back tasks.

Individual trajectories (red) of the average percent signal change derived for each subject with concussion in each of the three sessions for the cluster in left BA46 (mask derived from the 2 minus 1 contrast, α≤0.01 for each session). The median of the concussed (black) and controls (blue) are overlaid. Color image is available online at www.liebertpub.com/neu

Between group comparison (concussed–controls), for the 2 minus 1 n-back contrast, demonstrated persistent, significantly increased (α≤0.01, corrected) activity in bilateral, dorsolateral prefrontal areas throughout all three time points and in the left inferior parietal area within 72 hours and at 2 weeks post-injury. Images are shown in radiological convention (right=subject's left) for slice coordinates: x=−48 mm, y=32 mm, z=12 mm. Color image is available online at www.liebertpub.com/neu