PMC

Summary of ¹⁸F-FDG PET/CT findings and follow-up results in the 32 cases of tumor marker elevation of treated cervix malignancy. LN: lymph node.

True-positive case (splenic metastasis). A 54-year-old female had treated cervical cancer (squamous cell carcinoma). One year later, serum SCC Ag was elevated (from 1.4 to 3.2 ng/ml in 1 month). Contrast-enhanced abdomen CT (A) was done but recurrence of metastasis was not revealed. After 1 week, ¹⁸F-FDG PET/CT (B, C) detected a hypermetabolic lesion of max SUV 8.9 in the spleen (B, C arrows). Metastasis was confirmed by biopsy.

True-positive case (lymph node metastasis). A 72-year-old female had a cervical malignancy (squamous cell carcinoma) treated with chemoradiation therapy. Four months after the last treatment, serum SCC Ag was elevated (8.8 ng/ml). Pelvic CT (A) was done, but no metastatic lesions were detected. After 1 month, ¹⁸F-FDG PET/CT was done (B, C). Hypermetabolic lymph nodes with max SUV 5.0 were detected in the paraaortic area (B, C arrows). These lymph nodes were supposed to be benign lesions in the previous CT (A, arrow). Recurrence was clinically confirmed by follow-up CT studies and chemotherapy was done for this patient.