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1.
Figure 6

Figure 6. From: MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

Comparison between MirSNP and three similar databases.

Chenxing Liu, et al. BMC Genomics. 2012;13:661-661.
2.
Figure 1

Figure 1. From: MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

Workflow depicting analysis of variations in/near miRNA genes.

Chenxing Liu, et al. BMC Genomics. 2012;13:661-661.
3.
Figure 5

Figure 5. From: MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

The “Query disease & trait associated SNPs” frame of the MirSNP web site.

Chenxing Liu, et al. BMC Genomics. 2012;13:661-661.
4.
Figure 4

Figure 4. From: MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

(A) The “Single search” frame of the MirSNP web site. (B) An example of miRNA-related SNP search results.

Chenxing Liu, et al. BMC Genomics. 2012;13:661-661.
5.
Figure 3

Figure 3. From: MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

(A) Workflow depicting the analysis of variations in miRNA-mRNA binding sites.(B) An example of how we determinate a SNP in predicted mRNA target site.

Chenxing Liu, et al. BMC Genomics. 2012;13:661-661.
6.
Figure 2

Figure 2. From: MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs.

Density of SNPs in human miRNA genes. (A) SNP density in human pre-miRNAs and flanking regions. Each bar represents the average level of all human miRNAs, error bars represent the standard deviation of the mean value. MiRNA and SNP information came from mirBASE18 and dbSNP135, respectively. Figure A shows the result of all SNPs in dbSNP135. (B) Figure B only shows SNPs with a calculated MAF > 0.01 in at least one population from four (CEU, HCB, JPT, YRI).

Chenxing Liu, et al. BMC Genomics. 2012;13:661-661.

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