PMC

Hospitalizations and Spending for Severe Sepsis and Acute Myocardial Infarction in Medicare. Spending is for the acute hospitalization only and is not inflation-adjusted.

Case Fatality Rates After Severe Sepsis, by year in which severe sepsis developed. The case fatality rate is the fraction of hospitalizations after which the patient died by the specified time period.

New 3-Year and 5-Year Survivors After Severe Sepsis. shows the relative contributions of increasing rates of organ dysfunction per hospitalization with infection, increasing rates of hospitalization with infection, population aging and changes in the 3-year case fatality to these trends.

Contributions to the Rising Number of Survivors of Severe Sepsis. This Figure shows the relative number of 3-year survivors who would have been expected had only each given factor changed.
Interpretive Example: The aging of the population alone would have resulted in a 5.7% increase in the number of 3-year survivors between 1999 and 2008, had other rates remained the same. The Figure reveals that the most important contributor to the growth in the number of severe sepsis survivors over this decade was the increase in the rate of organ dysfunction per patient hospitalized with infection, not by better survival among patients with severe sepsis.