Comparison of plasma thrombospondin-1 (TSP-1) levels. A: patients were divided into four groups to compare plasma TSP-1 levels. Statistical analysis showed that TSP-1 levels were highest in the DM(+)CAD(+) group. B: when patients were divided into two groups according to the presence of DM, plasma levels of TSP-1 were higher in the DM group than those in the non-DM group (577.9±104.5 ng/mL vs. 519.3±123.5 ng/mL, p<0.001). C: when patients were divided into two groups according to CAD, plasma levels of TSP-1 were not significantly different between the non-CAD and CAD groups (532.4±117.0 ng/mL vs. 552.7±120.2 ng/mL, p=0.091). DM(-)CAD(-): patients without DM and without CAD, DM(-)CAD(+): patients without DM and with CAD, DM(+)CAD(-): patients with DM but without CAD, DM(+)CAD(+): patients with DM and CAD, TSP-1: thrombospodin-1, DM: diabetes mellitus, CAD: coronary artery disease.