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1.
Figure 2

Figure 2. Vaccination events by days since birth from days 340 to 700.. From: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis.

Count = number of individuals vaccinated on a given day. Days = number of days after date of birth.

Kumanan Wilson, et al. PLoS One. 2011;6(12):e27897.

CitationFull text

2.
Figure 4

Figure 4. Number of combined endpoints versus days before/after 18 month vaccination.. From: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis.

Count = number of combined endpoints of emergency room visit or hospitalization. Days = number of days before or after vaccination, day 0 being the day of vaccination.

Kumanan Wilson, et al. PLoS One. 2011;6(12):e27897.

CitationFull text

3.
Figure 3

Figure 3. Number of combined endpoints versus days before/after 12 month vaccination.. From: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis.

Count = number of combined endpoints of emergency room visit or hospitalization. Days = number of days before or after vaccination, day 0 being the day of vaccination.

Kumanan Wilson, et al. PLoS One. 2011;6(12):e27897.

CitationFull text

4.
Figure 5

Figure 5. Historical analysis of combined endpoints versus days following 12 and 18 month vaccination: April 2002–March 2005.. From: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis.

a) Before/after 12 month vaccination. b) Before/after 18 month vaccination. Count = number of combined endpoints of emergency room visit or hospitalization. Days = number of days before or after vaccination, day 0 being the day of vaccination.

Kumanan Wilson, et al. PLoS One. 2011;6(12):e27897.

CitationFull text

5.
Figure 1

Figure 1. Illustration of the self-controlled case series design.. From: Adverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis.

The observation period for each patient begins with pediatric vaccination date (leftmost upward arrow) and continues for a total of 28 days. In the primary analyses, each day post vaccination is considered a risk interval, and consecutive days with a statistically significant t elevation in relative incidence were pooled to create a combined risk interval. Days 20–28 comprise the control interval. The intervening days represent the wash-out period.

Kumanan Wilson, et al. PLoS One. 2011;6(12):e27897.

CitationFull text

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