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1.
Fig. 1

Fig. 1. Median (interquartile range) whole-blood (○) and plasma (●) concentrations following smoking of a 6.8% THC cannabis cigarette. From: Identification of Recent Cannabis Use: Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics following Controlled Smoked Cannabis Administration.

Samples collected at −0.5, 0.25, 0.5, 1.0, 2.0, 3.0, 4.0, 6.0, and 22 h after starting smoking. Dotted lines indicate limits of quantification: 1 μg/L for THC, 11-OH-THC, THCCOOH, CBD, and CBN; 0.5 μg/L for THC-glucuronide (THC-gluc) and 5 μg/L for THCCOOH-glucuronide (THCCOOH-gluc).

David M. Schwope, et al. Clin Chem. ;57(10):1406-1414.

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2.
Fig. 3

Fig. 3. Cannabinoid detection rates following a single smoked 6.8% THC cannabis cigarette in whole blood (A) and plasma (B). n = 9, 6, and 10 at 0.25 h, 22 h, and all other times, respectively. From: Identification of Recent Cannabis Use: Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics following Controlled Smoked Cannabis Administration.

All samples contained THCCOOH and THCCOOH-glucuronide. Limits of quantification: 1 μg/L for THC, 11-OH-THC, CBD, CBN, and THCCOOH; 0.5 μg/L for THC-glucuronide; 5.0 μg/L for THCCOOH-glucuronide.

David M. Schwope, et al. Clin Chem. ;57(10):1406-1414.

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3.
Fig. 2

Fig. 2. Median (interquartile range) molar whole-blood (○) and plasma (●) [glucuronide]/[free] ratios for THC (A) and THCCOOH (B) following a 6.8% THC cannabis cigarette. n values indicate data points for THC; for THCCOOH, n = 9, 6, and 10 at 0.25 h, 22 h, and all other times, respectively. From: Identification of Recent Cannabis Use: Whole-Blood and Plasma Free and Glucuronidated Cannabinoid Pharmacokinetics following Controlled Smoked Cannabis Administration.

THC-glucuronide was <LOQ (0.5 μg/L) after 1 h in whole blood and 4.0 h in plasma. *P < 0.05 compared to baseline, Tukey HSD.

David M. Schwope, et al. Clin Chem. ;57(10):1406-1414.

CitationFull text

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