PMC

Open field locomotion assessed by the BBB scale in the four groups of rats tested. All groups are significantly different (p<0.05) from day 7 to the end of the follow-up.

Dorsal and plantar surfaces of fore (A, B) and hind paws (C, D), with black arrows indicating the point of application of the mechanical stimuli in the Randall-Selitto test. (E) Application of the tip of the Randall-Selitto probe during a test.

Randall-Selitto measurements to assess neuropathic pain responses. Results are expressed as percentage of control values. Note that animals with spinal cord contusions show a slightly different pattern of hyperalgesic response than animals with complete transection. Dashed line represents the control values in each graph. Statistical significance: *p<0.05 vs. control group; #, p<0.05 vs. complete section; $, p<0.05 vs. 200 kdyn.