PMC

Risk of incident myocardial infarction according to categories of leisure-time physical activity level and genotype score at the LPL (1A), LIPC (1B), and CETP (1C) loci. Women with at least one copy of the minor allele at each locus were defined as having a beneficial genotype at that locus, while those homozygous for the major allele were defined as having a deleterious genotype at that locus. Compared to those with a deleterious genotype score, high-density lipoprotein cholesterol levels among those with a beneficial genotype score at LPL (rs10096633) were 1.75 mg/dl higher, at LIPC (rs1800588) were 2.3 mg/dL higher, and at CETP (rs1800588) were 3.73 mg/dL higher (Each P<0.0001).