PMC

Statistical parametric maps of significantly increased regional cerebral blood flow (rCBF) in PTSD relative to controls.

Representative maps of regional cerebral blood flow (rCBF - after fusion with structural MRI and partial volume correction) from two trauma exposed veterans, one diagnosed with PTSD (PTSD+, age =34 years, CAPS = 80) and another without PTSD (PTSD-, age = 22 years, CAPS = 13). The arrows in the rCBF maps point to the inferior posterior lobule, which showed a systematic increase in rCBF in PTSD.

Statistical maps of significant reduction in fractional anisotropy (FA, shown in blue) in PTSD relative to control subjects (p = 0.001, uncorrected). Areas of significant FA reduction include regions near the anterior cingulate cortex (ACC), prefrontal cortex (PFC), posterior central gyrus (PCG) and angular gyrus (AG). FA reductions in PTSD are also seen in the posterior internal capsule (pIC). FA increase (orange) is seen at a single location in an unspecific anatomical region (far right image in the top row).