PMC

An example of the estimated transition point.

Selection of the study cohort from the BLSA.

Cumulative percentage of men with a PSA transition point: (a) by time before diagnosis; and (b) by age at the transition point. The solid line depicts men who did not and the dotted line depicts those who did die from prostate cancer.

Distributions of PSAV levels and PSA at the transition point for men who did and did not die from prostate cancer. (A) Distribution of PSAV; (B) Distribution of PSA levels. Boxes represent the 25th to 75th percentiles (IQR); horizontal lines within boxes are the median values; vertical lines are 1.5 times the IQR (outliers of > 1.5 times the IQR were removed from illustration).