PMC

Pathways of naphthalene metabolism.

Comparable mechanisms of cancer initiation by natural estrogens and naphthalene.

Formation of depurinating adducts in mouse skin treated with naphthalene or one of its metabolites. The values are the average of two determinations that differed by <20%.

Quantitative comparison of depurinating and stable adducts formed in mouse skin treated with naphthalene (500 or 1200 nmol) or one of its metabolites (500 nmol). The values are an average of two determinations that differed by <20%.

PAGE analysis of ³²P-postlabeled stable DNA adducts obtained from naphthalene and its metabolites in vitro and in vivo. For the in vivo study, naphthalene (1200 or 500 nmol) or its metabolite (500 nmol) was delivered in 50 μl acetone to mouse skin.