PMC

Effect of lemon polyphenols on body weight gain (A) and cumulative energy intake (B) of the mice fed the experimental diets for 12 weeks.
The data represent the body weight gain and energy intake of low-fat diet (open circles), the high-fat diet (closed circles), and the high-fat diet supplemented with lemon polyphenols (closed squares). Data are mean ± SD. n = 6–7 in each group. *p<0.05 indicates significant differences from the mice fed the high-fat diet.

The mRNA levels of PPARα, β-oxidation and lipogenic-related gene in the liver and WAT from mice fed experimental diets for 12 weeks. The mice were fed the experimental diets for 12 weeks. After overnight fasting they were sacrificed. Hepatic and adipose mRNA was prepared for quantitative PCR analysis. (A)The PPARα, its downstream gene involved in fatty acid oxidation (B)ACO, (C)MCAD, and the lipogenic related gene (D) FAS were measured by quantitative PCR. Data are expressed as mean ± SD. n = 6 in each group. Values with different superscripts are significantly different, p<0.05.