U.S. flag

An official website of the United States government

PMC Full-Text Search Results

Items: 3

1.
Figure 3

Figure 3. From: Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

Power of the meta-analysis to identify each of the ten colorectal cancer susceptibility alleles, stipulating a P value of 10−5. Genotypic risks associated with each locus derived from replication data.

. Nat Genet. ;40(12):1426-1435.
2.
Figure 2

Figure 2. From: Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

Forest plot of effect size and direction for the four SNPs associated with CRC. (a) rs961253. (b) rs4444235. (c) rs10411210. (d) rs9929218. Boxes denote allelic OR point estimates, their areas being proportional to the inverse variance weight of the estimate. Horizontal lines represent 95% CIs. The diamond (and broken line) represents the summary OR computed under a fixed-effects model, with the 95% CI given by its width. The unbroken vertical line is at the null value (OR = 1.0).

. Nat Genet. ;40(12):1426-1435.
3.
Figure 1

Figure 1. From: Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.

Regional plots of the four confirmed associations (14q22.2, 16q22.1, 19q13.1 and 20p12.3). Each panel shows single-marker association statistics (as −log10 P) from the combined analysis of phase 1 (red), phases 1 and 2 (blue) and all phases (yellow) as a function of genomic position (NCBI build 36.1). Recombination rate across each region in HapMap CEU shown in black (right y axis). Also shown are the relative position of genes mapping to each region of association.

. Nat Genet. ;40(12):1426-1435.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center