U.S. flag

An official website of the United States government

Display Settings:

Items per page
You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 6

1.
Figure 1

Figure 1. Intensity across centers.. From: Randomization in Laboratory Procedure Is Key to Obtaining Reproducible Microarray Results.

Median intensity (a) and Median absolute deviation across centers (b). Samples from each center are individually RMA processed.

Hyuna Yang, et al. PLoS One. 2008;3(11):e3724.

CitationFull text

2.
Figure 5

Figure 5. Principal component analysis is applied to data from each center, and first and second principal components are plotted.. From: Randomization in Laboratory Procedure Is Key to Obtaining Reproducible Microarray Results.

Hyuna Yang, et al. PLoS One. 2008;3(11):e3724.

CitationFull text

3.
Figure 4

Figure 4. DE genes are selected by rank of Fs test statistics.. From: Randomization in Laboratory Procedure Is Key to Obtaining Reproducible Microarray Results.

The proportion of genes shared by centers when strain (a) and sex (b) being tested.

Hyuna Yang, et al. PLoS One. 2008;3(11):e3724.

CitationFull text

4.
Figure 6

Figure 6. Sample clustering of original data (a).. From: Randomization in Laboratory Procedure Is Key to Obtaining Reproducible Microarray Results.

Using center 3 and center 4 as training set, get the H matrix (containing expression level of metagene from each sample), project the metagene to each center and cluster the projected data (b and c respectively).

Hyuna Yang, et al. PLoS One. 2008;3(11):e3724.

CitationFull text

5.
Figure 3

Figure 3. Number of significantly differentially expressed (DE) genes in each chromosome selected by q-value<0.05.. From: Randomization in Laboratory Procedure Is Key to Obtaining Reproducible Microarray Results.

Panel a shows the DE genes from the overall test, and Panel b to f show the DE genes from the pairwise strain comparisons from each center. Center 4 and 5 have higher number of DE genes across all chromosomes. Panel e and f show higher number of DE genes in center 4 (B vs. A16) and center 5 (A15 vs. A1 or A6).

Hyuna Yang, et al. PLoS One. 2008;3(11):e3724.

CitationFull text

6.
Figure 2

Figure 2. Number of differentially expressed (DE) genes having strain (a, b and c) and sex effect (d, e and f).. From: Randomization in Laboratory Procedure Is Key to Obtaining Reproducible Microarray Results.

Number of DE genes selected by p-value (a and b), focusing on up to p-value<0.001 (c and d) and q-value (e and f). Center 4 and 5 have higher number of DE genes when strain effect was tested. However, Center 4 has smaller number of genes than other centers until p-value<2e-04 (panel c), then the number of gets increased, and that causes sudden increase in q-value (panel e). When sex effect is tested, center 2 and 3 show higher number of DE genes than other centers, however the difference is not as big as that of strain effect.

Hyuna Yang, et al. PLoS One. 2008;3(11):e3724.

CitationFull text

Display Settings:

Items per page

Supplemental Content

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center