PMC

Bland-Altman plot to assess agreement between GFR and estimated creatinine clearance (n = 35 pairs). The solid line represents the bias of the difference between pairs (17.8 ml/min per 1.73 m²) and the dashed lines represent the 95% confidence interval.

Renal tubular function was longitudinally assessed by measuring urinary magnesium excretion (a), renal tubular threshold for phosphate (b), and urinary β₂-microglobulin (c) in patients with Wilms tumour treated with ICE. Shaded areas (a, b) represent the normal range.

V=vincristine 1.5 mg/m² (maximum dose, 2 mg); D=dactinomycin 0.6 mg/m² (maximum dose, 2 mg); A=doxorubicin (Adriamycin) 25 mg/m²; ICE chemotherapy: C=carboplatin, dosage based on GFR to target an AUC of 6 mg/ml × min on day 1; E=etoposide 100 mg/m² per day on days 2–4; I=ifosfamide 2 g/m² per day on days 2–4.