The clustering identified 4 distinct clusters indicated as A, B, C, and DE. Clusters D and E could not be separated in this series. Clinical annotations are at the bottom. Thompson subtypes as indicated in their paper: yellow = Thompson subtype A, light pink = Thompson subtype B, blue = Thompson subtype C, green = Thompson subtype D, dark pink = Thompson subtype E; Histology: grey = desmoplastic, orange = large cell/anaplastic, white = classic; sex: pink = female, white = male; M stage: yellow = M1, orange = ≥M2, white = M0; Age: purple = age ≤3 yrs, white = age >3 yrs; β-catenin mutations: brown = mutations, white = wild type; PTCH1/SUFU mutations: light blue = PTCH1 mutations, dark blue = SUFU mutation, white = wild type; 17p deletions: dark red = yes, white = no. A cross means not analyzed.