PMC

Computational model of a large portion of the human infrarenal aorta including an abdominal aortic aneurysm. Shown too are estimated velocity distributions based on a FSI simulation of both rest and exercise.

Computational model of a large portion of the human circle of Willis including an intracranial saccular aneurysm. Shown too are estimated velocity distributions based on a FSI simulation.

Schema of the proposed Fluid-Solid-Growth (FSG) modeling approach: fluid-solid interaction (FSI) computations of the hemodynamics (time scale of seconds) provide updated information on wall tractions for the biosolid mechanics computations of G&R (time scale of days to weeks or years), which in turn provide updated information on changing geometry and material properties for the FSI code. The solution iterates between the hemodynamics and wall mechanics until either the vasculature achieves a steady state or a vessel or lesion ruptures. Modified from Figueroa et al. ().