PMC

A: Carotid artery angiogram obtained 1 week after creating CA sidewall aneurysms just prior to coil embolization. B: Carotid artery angiogram obtained 1 week after creation of CA side-wall aneurysms following coil embolization.

Endoluminal view of 27-day aneurysm treated with Matrix coils during OCT imaging. Horizontal lines demonstrate how OCT scans across the neck of the aneurysm; the resulting nine scans are shown in .

Photograph depicting an aneurysm 7 days after embolization with uncoated platinum coils. After excision, the artery was opened longitudinally and sutured into an acrylic block with a central well to hold the aneurysm.

Schematic of the bench-top OCT system. The aneurysm specimen is immersed in saline solution in a glass cuvette (shown from above) to minimize light reflection from the surface. SLD = super luminescent diode.

Graph demonstrating measurements of overlying tissue thickness based on images shown in . These data depict the results listed in (error bars show one standard deviation above and below the mean).

Histological specimens and corresponding OCT image, respectively, across the central aspect of the aneurysm treated with GDCs at 7 days (a and b), Matrix coils at 7 days (c and d), GDCs at 27 days (e and f), and Matrix coils at 27 days (g and h).

Stacked OCT images of experimental sidewall CA aneurysms in dogs examined 7 (a) and 27 (b) days after embolization with GDCs or Matrix coils. Each image covers an area of 2.3 mm (depth) × 9.8 mm (length). The images were recorded at a separation of 0.4 mm, but are displayed here at much greater spacing to avoid visual overlap.

Optical coherence tomography images obtained across the central aspect of the experimental aneurysm 7 (a), 15 (b), 21 (c), and 27 (d) days after coil embolization. For scale comparison, the size of the platinum coils is shown in the lower left corner of each image.