PMC Articles for MedGen (Select 79016) - PMC

Select item 100389091.

Pathologic, Cytogenetic, and Molecular Features of Acute Myeloid Leukemia with Megakaryocytic Differentiation: a Report from the Children’s Oncology Group

Karen M. Chisholm, Jenny Smith, Amy E. Heerema-McKenney, John K. Choi, Rhonda E. Ries, Betsy A. Hirsch, Susana C. Raimondi, Yi-Cheng Wang, Alice Dang, Todd A. Alonzo, Lillian Sung, Richard Aplenc, Alan S. Gamis, Soheil Meshinchi, Samir B. Kahwash

Pediatr Blood Cancer. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Pediatr Blood Cancer. 2023 May; 70(5): e30251. Published online 2023 Feb 15. doi: 10.1002/pbc.30251

PMCID:: PMC10038909

Abstract Article PDF–1.1M

Select item 72691982.

KLF1/EKLF expression in acute leukemia is correlated with chromosomal abnormalities

Adnan Mansoor, Mohammad Omer Mansoor, Jay L Patel, Shuchun Zhao, Yasodha Natkunam, James J Bieker

Blood Cells Mol Dis. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Blood Cells Mol Dis. 2020 Jul; 83: 102434. Published online 2020 Apr 13. doi: 10.1016/j.bcmd.2020.102434

PMCID:: PMC7269198

Abstract Article PDF–1.2M

Select item 69413983.

TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

Keiichi Akizuki, Masaaki Sekine, Yasunori Kogure, Takuro Kameda, Kotaro Shide, Junji Koya, Ayako Kamiunten, Yoko Kubuki, Yuki Tahira, Tomonori Hidaka, Takumi Kiwaki, Hiroyuki Tanaka, Yuichiro Sato, Hiroaki Kataoka, Keisuke Kataoka, Kazuya Shimoda

BMC Cancer. 2020; 20: 5. Published online 2020 Jan 2. doi: 10.1186/s12885-019-6497-0

PMCID:: PMC6941398

Abstract Article PDF–5.6M

Select item 66744634.

Role of Megakaryoblastic Acute Leukemia-1 in ERK1/2-Dependent Stimulation of Serum Response Factor-Driven Transcription by BDNF or Increased Synaptic Activity

Katarzyna Kalita, Giorgi Kharebava, Jing-Juan Zheng, Michal Hetman

J Neurosci. 2006 Sep 27; 26(39): 10020–10032. doi: 10.1523/JNEUROSCI.2644-06.2006

Correction in:: J Neurosci. 2007 Mar 21; 27(12): np.

PMCID:: PMC6674463

Abstract Article PDF–901K

Select item 65903515.

CBFA2T3‐GLIS2‐positive acute myeloid leukaemia. A peculiar paediatric entity

Riccardo Masetti, Salvatore N. Bertuccio, Andrea Pession, Franco Locatelli

Br J Haematol. 2019 Feb; 184(3): 337–347. Published online 2018 Dec 28. doi: 10.1111/bjh.15725

PMCID:: PMC6590351

Abstract Article PDF–407K

Select item 56878246.

Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia is Characterized by Distinct Genomic Subsets with Varying Outcomes

Jasmijn D.E. de Rooij, Cristyn Branstetter, Jing Ma, Yongjin Li, Michael P. Walsh, Jinjun Cheng, Askar Obulkasim, Jinjun Dang, John Easton, Lonneke J. Verboon, Heather L. Mulder, Martin Zimmermann, Cary Koss, Pankaj Gupta, Michael Edmonson, Michael Rusch, Joshua Yew Suang Lim, Katarina Reinhardt, Martina Pigazzi, Guangchun Song, Allen Eng Juh Yeoh, Lee-Yung Shih, Der-Cherng Liang, Stephanie Halene, Diane S. Krause, Jinghui Zhang, James R. Downing, Franco Locatelli, Dirk Reinhardt, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan, Maarten Fornerod, Tanja A. Gruber

Nat Genet. Author manuscript; available in PMC 2017 Nov 15.

Published in final edited form as: Nat Genet. 2017 Mar; 49(3): 451–456. Published online 2017 Jan 23. doi: 10.1038/ng.3772

PMCID:: PMC5687824

Abstract Article PDF–1.1M

Select item 40680047.

The most informative spacing test effectively discovers biologically relevant outliers or multiple modes in expression

Iwona Pawlikowska, Gang Wu, Michael Edmonson, Zhifa Liu, Tanja Gruber, Jinghui Zhang, Stan Pounds

Bioinformatics. 2014 May 15; 30(10): 1400–1408. Published online 2014 Jan 22. doi: 10.1093/bioinformatics/btu039

PMCID:: PMC4068004

Abstract Article PDF–393K

Select item 35476678.

An inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia

Tanja A. Gruber, Amanda Larson Gedman, Jinghui Zhang, Cary S. Koss, Suresh Marada, Huy Q. Ta, Shann-Ching Chen, Xiaoping Su, Stacey K. Ogden, Jinjun Dang, Gang Wu, Vedant Gupta, Anna K. Andersson, Stanley Pounds, Lei Shi, John Easton, Michael I. Barbato, Heather L. Mulder, Jayanthi Manne, Jianmin Wang, Michael Rusch, Swati Ranade, Ramapriya Ganti, Matthew Parker, Jing Ma, Ina Radtke, Li Ding, Giovanni Cazzaniga, Andrea Biondi, Steven M. Kornblau, Farhad Ravandi, Hagop Kantarjian, Stephen D. Nimer, Konstanze Döhner, Hartmut Döhner, Timothy J. Ley, Paola Ballerini, Sheila Shurtleff, Daisuke Tomizawa, Souichi Adachi, Yasuhide Hayashi, Akio Tawa, Lee-Yung Shih, Der-Cherng Liang, Jeffrey E. Rubnitz, Ching-Hon Pui, Elaine R Mardis, Richard K Wilson, James R. Downing

Cancer Cell. Author manuscript; available in PMC 2013 Nov 13.

Published in final edited form as: Cancer Cell. 2012 Nov 13; 22(5): 683–697. doi: 10.1016/j.ccr.2012.10.007

PMCID:: PMC3547667

Abstract Article PDF–4.3M

Select item 34789329.

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

Clarisse Thiollier, Cécile K. Lopez, Bastien Gerby, Cathy Ignacimouttou, Sandrine Poglio, Yannis Duffourd, Justine Guégan, Paola Rivera-Munoz, Olivier Bluteau, Vinciane Mabialah, M’Boyba Diop, Qiang Wen, Arnaud Petit, Anne-Laure Bauchet, Dirk Reinhardt, Beat Bornhauser, Daniel Gautheret, Yann Lecluse, Judith Landman-Parker, Isabelle Radford, William Vainchenker, Nicole Dastugue, Stéphane de Botton, Philippe Dessen, Jean-Pierre Bourquin, John D. Crispino, Paola Ballerini, Olivier A. Bernard, Françoise Pflumio, Thomas Mercher

J Exp Med. 2012 Oct 22; 209(11): 2017–2031. doi: 10.1084/jem.20121343

PMCID:: PMC3478932

Abstract Article PDF–3.6M

Select item 328738210.

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome

Sébastien Malinge, Meghan Bliss-Moreau, Gina Kirsammer, Lauren Diebold, Timothy Chlon, Sandeep Gurbuxani, John D. Crispino

J Clin Invest. 2012 Mar 1; 122(3): 948–962. Published online 2012 Feb 22. doi: 10.1172/JCI60455

PMCID:: PMC3287382

Abstract Article PDF–2.4M

Select item 328723811.

DYRK1A in Down syndrome: an oncogene or tumor suppressor?

Yehudit Birger, Shai Izraeli

J Clin Invest. 2012 Mar 1; 122(3): 807–810. Published online 2012 Feb 22. doi: 10.1172/JCI62372

PMCID:: PMC3287238

Abstract Article PDF–659K

Select item 324392812.

Myeloid Leukemia in Down Syndrome

Irum Khan, Sébastien Malinge, John D. Crispino

Crit Rev Oncog. Author manuscript; available in PMC 2012 Jan 1.

Published in final edited form as: Crit Rev Oncog. 2011; 16(1-2): 25–36. doi: 10.1615/critrevoncog.v16.i1-2.40

PMCID:: PMC3243928

Abstract Article PDF–500K

Select item 322866613.

De novo acute megakaryoblastic leukemia with p210 BCR/ABL and t(1;16) translocation but not t(9;22) Ph chromosome

Xiao Min, Zhang Na, Liu Yanan, Li Chunrui

J Hematol Oncol. 2011; 4: 45. Published online 2011 Nov 10. doi: 10.1186/1756-8722-4-45

PMCID:: PMC3228666

Abstract Article PDF–811K

Select item 316371814.

Identification of a Novel, Tissue-Specific ABCG2 Promoter Expressed in Pediatric Acute Megakaryoblastic Leukemia

Patrick K. Campbell, Yang Zong, Shengping Yang, Sheng Zhou, Jeffrey E. Rubnitz, Brian P. Sorrentino

Leuk Res. Author manuscript; available in PMC 2012 Oct 1.

Published in final edited form as: Leuk Res. 2011 Oct; 35(10): 1321–1329. doi: 10.1016/j.leukres.2011.05.004

PMCID:: PMC3163718

Abstract Article PDF–1.3M

Select item 315434815.

Development of Acute Megakaryoblastic Leukemia with Isochromosome (12p) after a Primary Mediastinal Germ Cell Tumor in Korea

Nae Yu, Hye Ryoun Kim, Young-Joo Cha, Eun Kyung Park, Jeong Wook Kim

J Korean Med Sci. 2011 Aug; 26(8): 1099–1102. Published online 2011 Jul 28. doi: 10.3346/jkms.2011.26.8.1099

PMCID:: PMC3154348

Abstract Article PDF–2.3M

Select item 274457016.

c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development

Chao Niu, Jiwang Zhang, Peter Breslin, Mihaela Onciu, Zhigui Ma, Stephan Wade Morris

Blood. 2009 Sep 3; 114(10): 2087–2096. Prepublished online 2009 Jun 19. doi: 10.1182/blood-2009-01-197921

PMCID:: PMC2744570

Abstract Article

Select item 185160617.

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Glen D. Raffel, Thomas Mercher, Hirokazu Shigematsu, Ifor R. Williams, Dana E. Cullen, Koichi Akashi, Olivier A. Bernard, D. Gary Gilliland

Proc Natl Acad Sci U S A. 2007 Apr 3; 104(14): 6001–6006. Published online 2007 Mar 21. doi: 10.1073/pnas.0609041104

PMCID:: PMC1851606

Abstract Article PDF–1.3M

Select item 180121518.

Cytogenetic and molecular studies of Down syndrome individuals with leukemia.

J J Shen, B J Williams, A Zipursky, J Doyle, S L Sherman, P A Jacobs, A L Shugar, S W Soukup, T J Hassold

Am J Hum Genet. 1995 Apr; 56(4): 915–925.

PMCID:: PMC1801215

Summary Page Browse PDF–1.8M

Select item 159992619.

A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia

Ian J. Majewski, Donald Metcalf, Lisa A. Mielke, Danielle L. Krebs, Sarah Ellis, Marina R. Carpinelli, Sandra Mifsud, Ladina Di Rago, Jason Corbin, Nicos A. Nicola, Douglas J. Hilton, Warren S. Alexander

Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38): 14146–14151. Published online 2006 Sep 11. doi: 10.1073/pnas.0606439103

PMCID:: PMC1599926

Abstract Article PDF–970K

Select item 291256320.

Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis

Jan-Henning Klusmann, Frank J. Godinho, Kirsten Heitmann, Aliaksandra Maroz, Mia Lee Koch, Dirk Reinhardt, Stuart H. Orkin, Zhe Li

Genes Dev. 2010 Aug 1; 24(15): 1659–1672. doi: 10.1101/gad.1903410

PMCID:: PMC2912563

Abstract Article PDF–1.4M

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