PMC Articles for MedGen (Select 507002) - PMC

Result Filters

Links from MedGen

Items: 1 to 20 of 284

<< First< Prev

Page of 15

Select item 111430071.

Unveiling cellular and molecular aspects of ascending thoracic aortic aneurysms and dissections

Berta H. Ganizada, Rogier J. A. Veltrop, Asim C. Akbulut, Rory R. Koenen, Ryan Accord, Roberto Lorusso, Jos G. Maessen, Koen Reesink, Elham Bidar, Leon J. Schurgers

Basic Res Cardiol. 2024; 119(3): 371–395. Published online 2024 May 3. doi: 10.1007/s00395-024-01053-1

PMCID:: PMC11143007

Abstract Article PDF–1.7M

Select item 110561232.

Gestational Hypoxia Impaired Endothelial Nitric Oxide Synthesis Via miR‐155‐5p/NADPH Oxidase/Reactive Oxygen Species Axis in Male Offspring Vessels

Meng Zhao, Jiahui Lei, Fengying Deng, Chenxuan Zhao, Ting Xu, Bingyu Ji, Mengyu Fu, Xietong Wang, Miao Sun, Meihua Zhang, Qinqin Gao

J Am Heart Assoc. 2024 Feb 6; 13(3): e032079. Published online 2024 Jan 19. doi: 10.1161/JAHA.123.032079

PMCID:: PMC11056123

Abstract Article PDF–13M

Select item 108701353.

STIGMA: Single-cell tissue-specific gene prioritization using machine learning

Saranya Balachandran, Cesar A. Prada-Medina, Martin A. Mensah, Juliane Glaser, Naseebullah Kakar, Inga Nagel, Jelena Pozojevic, Enrique Audain, Marc-Phillip Hitz, Martin Kircher, Varun K.A. Sreenivasan, Malte Spielmann

Am J Hum Genet. 2024 Feb 1; 111(2): 338–349. Published online 2024 Jan 15. doi: 10.1016/j.ajhg.2023.12.011

Correction in:: Am J Hum Genet. 2024 Mar 7; 111(3): 618.

PMCID:: PMC10870135

Abstract Article PDF–3.2M

Select item 106082394.

Perinatal Diagnosis and Management of a Case with Interrupted Aortic Arch, Pulmonary Valve Dysplasia and 22q11.2 Deletion: A Case Report

Radu Vlădăreanu, Călina Maier, Raluca Tocariu, Marcela Șerban, Elvira Brătilă

Medicina (Kaunas) 2023 Oct; 59(10): 1838. Published online 2023 Oct 16. doi: 10.3390/medicina59101838

PMCID:: PMC10608239

Abstract Article PDF–2.0M

Select item 105341655.

Life-Threatening Aortic Dissection during Pregnancy: A Case Report of Undiagnosed FBN1-Related Marfan Syndrome at 39 Weeks Gestation

Carmelina Gurrieri, Westley T. Manske, Carla Williams, Joseph C. Wildenberg, Rachel J. Keppers, Tiziano Tallarita, Nishant Saran, Andrew D. Calvin

Am J Case Rep. 2023; 24: e940628-1–e940628-6. Published online 2023 Sep 25. doi: 10.12659/AJCR.940628

PMCID:: PMC10534165

Abstract Article PDF–1.3M

Select item 105277636.

TGFβ−2 haploinsufficiency causes early death in mice with Marfan syndrome

Nalani Sachan, Colin K.L. Phoon, Lior Zilberberg, Matthias C. Kugler, Taylor Ene, Shana B. Mintz, Sae-Il Murtada, Dar Weiss, Glenn I. Fishman, Jay D. Humphrey, Daniel B. Rifkin

Matrix Biol. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Matrix Biol. 2023 Aug; 121: 41–55. Published online 2023 May 20. doi: 10.1016/j.matbio.2023.05.004

PMCID:: PMC10527763

Abstract Article PDF–1.6M

Select item 104874617.

17 β-Estradiol Impedes Aortic Root Dilation and Rupture in Male Marfan Mice

Louis Saddic, Sean Escopete, Lior Zilberberg, Shannon Kalsow, Divya Gupta, Mansoureh Eghbali, Sarah Parker

Int J Mol Sci. 2023 Sep; 24(17): 13571. Published online 2023 Sep 1. doi: 10.3390/ijms241713571

PMCID:: PMC10487461

Abstract Article PDF–6.0M

Select item 103226838.

Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells

Yifei Sun, Keiichi Asano, Lauriane Sedes, Anna Cantalupo, Jens Hansen, Ravi Iyengar, Martin J. Walsh, Francesco Ramirez

JCI Insight. 2023 May 22; 8(10): e168793. Published online 2023 May 22. doi: 10.1172/jci.insight.168793

PMCID:: PMC10322683

Abstract Article PDF–2.3M

Select item 102181519.

NOTCH1 Gene as a Novel Cause of Thoracic Aortic Aneurysm in Patients with Tricuspid Aortic Valve: Two Cases Reported

Laura Torres-Juan, Yolanda Rico, Elena Fortuny, Jaume Pons, Rafael Ramos, Fernando Santos-Simarro, Víctor Asensio, Iciar Martinez, Damian Heine-Suñer

Int J Mol Sci. 2023 May; 24(10): 8644. Published online 2023 May 12. doi: 10.3390/ijms24108644

PMCID:: PMC10218151

Abstract Article PDF–940K

Select item 1017651410.

Central Nervous System and Cardiac Abnormalities in the Setting of a De Novo Heterozygous Col4a1 Variant

Heerali Patel, Mohammed Elkhwad, Gregory C. Martin

Am J Case Rep. 2023; 24: e938651-1–e938651-4. Published online 2023 May 9. doi: 10.12659/AJCR.938651

PMCID:: PMC10176514

Abstract Article PDF–491K

Select item 1010539011.

Excessive exogenous cholesterol activating intestinal LXRα-ABCA1/G5/G8 signaling pathway can not reverse atherosclerosis in ApoE^−/− mice

Xichao Yu, Xue Ding, Han Feng, Yunhui Bi, Yu Li, Jinjun Shan, Huimin Bian

Lipids Health Dis. 2023; 22: 51. Published online 2023 Apr 15. doi: 10.1186/s12944-023-01810-6

PMCID:: PMC10105390

Abstract Article PDF–5.6M

Select item 1002785512.

Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development

Christopher De Bono, Yang Liu, Alexander Ferrena, Aneesa Valentine, Deyou Zheng, Bernice E. Morrow

Nat Commun. 2023; 14: 1551. Published online 2023 Mar 21. doi: 10.1038/s41467-023-37015-9

PMCID:: PMC10027855

Abstract Article PDF–19M

Select item 1002444213.

Non-mosaic trisomy 22 and congenital heart surgery using the shared decision making model: a case report

Vivien Phung, Kathryn E. Singh, Saar Danon, Christopher A. Tan, Sarah Dabagh

BMC Pediatr. 2023; 23: 122. Published online 2023 Mar 18. doi: 10.1186/s12887-023-03949-8

PMCID:: PMC10024442

Abstract Article PDF–1.0M

Select item 997730314.

Ciprofloxacin exacerbates dysfunction of smooth muscle cells in a microphysiological model of thoracic aortic aneurysm

Bitao Xiang, Mieradilijiang Abudupataer, Gang Liu, Xiaonan Zhou, Dingqian Liu, Shichao Zhu, Yang Ming, Xiujie Yin, Shiqiang Yan, Yongxin Sun, Hao Lai, Chunsheng Wang, Jun Li, Kai Zhu

JCI Insight. 2023 Jan 24; 8(2): e161729. Published online 2023 Jan 24. doi: 10.1172/jci.insight.161729

PMCID:: PMC9977303

Abstract Article PDF–13M

Select item 996898815.

A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target

Hongorzul Davaapil, Madeline McNamara, Alessandra Granata, Robyn G.C. Macrae, Mei Hirano, Martina Fitzek, J.A. Aragon-Martin, Anne Child, David M. Smith, Sanjay Sinha

Stem Cell Reports. 2023 Feb 14; 18(2): 555–569. Published online 2023 Jan 19. doi: 10.1016/j.stemcr.2022.12.014

PMCID:: PMC9968988

Abstract Article PDF–4.2M

Select item 986532216.

Molecular Mechanisms in Genetic Aortopathy–Signaling Pathways and Potential Interventions

Charlotte Xue Dong, Cassandra Malecki, Elizabeth Robertson, Brett Hambly, Richmond Jeremy

Int J Mol Sci. 2023 Jan; 24(2): 1795. Published online 2023 Jan 16. doi: 10.3390/ijms24021795

PMCID:: PMC9865322

Abstract Article PDF–3.7M

Select item 985918717.

Improved Outcomes in Patients with 22q11.2 Deletion Syndrome and Diagnosis of Interrupted Aortic Arch Prior to Birth Hospital Discharge, a Retrospective Study

Hayley A. Ron, Terrence Blaine Crowley, Yichuan Liu, Marta Unolt, Erica Schindewolf, Julie Moldenhauer, Jack Rychik, Elizabeth Goldmuntz, Beverly S. Emanuel, Douglas Ryba, James William Gaynor, Elaine H. Zackai, Hakon Hakonarson, Donna M. McDonald-McGinn

Genes (Basel) 2023 Jan; 14(1): 62. Published online 2022 Dec 24. doi: 10.3390/genes14010062

PMCID:: PMC9859187

Abstract Article PDF–1.1M

Select item 980905418.

Induced pluripotent stem cells with NOTCH1 gene mutation show impaired differentiation into smooth muscle and endothelial cells: Implications for bicuspid aortic valve-related aortopathy

Jiao Jiao, Weihua Tian, Ping Qiu, Elizabeth L. Norton, Michael M. Wang, Y. Eugene Chen, Bo Yang

J Thorac Cardiovasc Surg. Author manuscript; available in PMC 2023 Jan 3.

Published in final edited form as: J Thorac Cardiovasc Surg. 2018 Aug; 156(2): 515–522.e1. Published online 2018 Mar 12. doi: 10.1016/j.jtcvs.2018.02.087

PMCID:: PMC9809054

Abstract Article PDF–1.2M

Select item 979755619.

Endothelial dysfunction in Marfan syndrome mice is restored by resveratrol

Arnout Mieremet, Miesje van der Stoel, Siyu Li, Evrim Coskun, Tsveta van Krimpen, Stephan Huveneers, Vivian de Waard

Sci Rep. 2022; 12: 22504. Published online 2022 Dec 28. doi: 10.1038/s41598-022-26662-5

PMCID:: PMC9797556

Abstract Article PDF–12M

Select item 977902420.

Impacts of Telomeric Length, Chronic Hypoxia, Senescence, and Senescence-Associated Secretory Phenotype on the Development of Thoracic Aortic Aneurysm

Thomas Aschacher, Daniela Geisler, Verena Lenz, Olivia Aschacher, Bernhard Winkler, Anne-Kristin Schaefer, Andreas Mitterbauer, Brigitte Wolf, Florian K. Enzmann, Barbara Messner, Günther Laufer, Marek P. Ehrlich, Martin Grabenwöger, Michael Bergmann

Int J Mol Sci. 2022 Dec; 23(24): 15498. Published online 2022 Dec 7. doi: 10.3390/ijms232415498