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Select item 99104581.

Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals

Hei Yeun Koo, Min-A Kim, Hyehyun Min, Jae Yeon Hwang, Meenakshi Prajapati-DiNubila, Kwan Soo Kim, Martin M. Matzuk, Juw Won Park, Angelika Doetzlhofer, Un-Kyung Kim, Jinwoong Bok

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2213099120. Published online 2022 Dec 28. doi: 10.1073/pnas.2213099120

PMCID:: PMC9910458

Abstract Article PDF–11M

Select item 96180522.

Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation

Tianli Qin, Chin Chung Ho, Boshi Wang, Chi-Chung Hui, Mai Har Sham

Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43): e2206571119. Published online 2022 Oct 17. doi: 10.1073/pnas.2206571119

PMCID:: PMC9618052

Abstract Article PDF–1.9M

Select item 95926043.

Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2

Young Rae Ji, Yosuke Tona, Talah Wafa, Matthew E. Christman, Edward D. Tourney, Tao Jiang, Sho Ohta, Hui Cheng, Tracy Fitzgerald, Bernd Fritzsch, Sherri M. Jones, Kathleen E. Cullen, Doris K. Wu

Nat Commun. 2022; 13: 6330. Published online 2022 Oct 24. doi: 10.1038/s41467-022-33819-3

PMCID:: PMC9592604

Abstract Article PDF–18M

Select item 92966664.

A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours

Akram A. Hamed, Daniel J. Kunz, Ibrahim El-Hamamy, Quang M. Trinh, Omar D. Subedar, Laura M. Richards, Warren Foltz, Garrett Bullivant, Matthaeus Ware, Maria C. Vladoiu, Jiao Zhang, Antony M. Raj, Trevor J. Pugh, Michael D. Taylor, Sarah A. Teichmann, Lincoln D. Stein, Benjamin D. Simons, Peter B. Dirks

Nat Commun. 2022; 13: 4178. Published online 2022 Jul 19. doi: 10.1038/s41467-022-31408-y

PMCID:: PMC9296666

Abstract Article PDF–11M

Select item 87137945.

Transcriptional network orchestrating regional patterning of cortical progenitors

Athéna R. Ypsilanti, Kartik Pattabiraman, Rinaldo Catta-Preta, Olga Golonzhka, Susan Lindtner, Ke Tang, Ian R. Jones, Armen Abnousi, Ivan Juric, Ming Hu, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio, Michael Hawrylycz, Carol L. Thompson, Hongkui Zeng, Iros Barozzi, Alex S. Nord, John L. Rubenstein

Proc Natl Acad Sci U S A. 2021 Dec 21; 118(51): e2024795118. Published online 2021 Dec 17. doi: 10.1073/pnas.2024795118

PMCID:: PMC8713794

Abstract Article PDF–3.1M

Select item 82137416.

Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors

Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Yan Wu, Adam J. Moeser, George I. Mias, Alfred J. Robison, Jin He

Commun Biol. 2021; 4: 756. Published online 2021 Jun 18. doi: 10.1038/s42003-021-02282-z

PMCID:: PMC8213741

Abstract Article PDF–3.2M

Select item 81379397.

Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2

Manuel Pedro Jimenez-García, Antonio Lucena-Cacace, Daniel Otero-Albiol, Amancio Carnero

Cell Death Dis. 2021 Jun; 12(6): 515. Published online 2021 May 20. doi: 10.1038/s41419-021-03801-w

PMCID:: PMC8137939

Abstract Article PDF–4.1M

Select item 81291418.

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

Katie S. Kindt, Anil Akturk, Amandine Jarysta, Matthew Day, Alisha Beirl, Michaela Flonard, Basile Tarchini

Nat Commun. 2021; 12: 2861. Published online 2021 May 17. doi: 10.1038/s41467-021-22997-1

PMCID:: PMC8129141

Abstract Article PDF–12M

Select item 77757619.

Abnormal neocortex arealization and Sotos-like syndrome–associated behavior in Setd2 mutant mice

Lichao Xu, Yue Zheng, Xuejing Li, Andi Wang, Dawei Huo, Qinglan Li, Shikang Wang, Zhiyuan Luo, Ying Liu, Fuqiang Xu, Xudong Wu, Min Wu, Yan Zhou

Sci Adv. 2021 Jan; 7(1): eaba1180. Published online 2021 Jan 1. doi: 10.1126/sciadv.aba1180

PMCID:: PMC7775761

Abstract Article PDF–11M

Select item 765971010.

Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling

Andre Landin Malt, Arielle K. Hogan, Connor D. Smith, Maxwell S. Madani, Xiaowei Lu

J Cell Biol. 2020 Oct 5; 219(10): e201912071. Published online 2020 Aug 17. doi: 10.1083/jcb.201912071

PMCID:: PMC7659710

Abstract Article PDF–5.1M

Select item 756148011.

Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea

Elvis Huarcaya Najarro, Jennifer Huang, Adrian Jacobo, Lee A. Quiruz, Nicolas Grillet, Alan G. Cheng

Development. 2020 Oct 1; 147(19): dev191981. Published online 2020 Oct 5. doi: 10.1242/dev.191981

PMCID:: PMC7561480

Abstract Article

Select item 753593312.

Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

Yosuke Tona, Doris K Wu

eLife. 2020; 9: e59282. Published online 2020 Sep 23. doi: 10.7554/eLife.59282

PMCID:: PMC7535933

Abstract Article PDF–14M

Select item 748706513.

Mdm4 controls ureteric bud branching via regulation of p53 activity

Sylvia A. Hilliard, Yuwen Li, Angelina Dixon, Samir S. El-Dahr

Mech Dev. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Mech Dev. 2020 Sep; 163: 103616. Published online 2020 May 25. doi: 10.1016/j.mod.2020.103616

PMCID:: PMC7487065

Abstract Article PDF–4.3M

Select item 740724514.

Regulation of Neurogenesis in Mouse Brain by HMGB1

Xiang Zhao, Ari Rouhiainen, Zhilin Li, Su Guo, Heikki Rauvala

Cells. 2020 Jul; 9(7): 1714. Published online 2020 Jul 17. doi: 10.3390/cells9071714

PMCID:: PMC7407245

Abstract Article PDF–4.8M

Select item 678681715.

Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons

Satish R. Ghimire, Michael R. Deans

J Neurosci. 2019 Oct 9; 39(41): 8013–8023. doi: 10.1523/JNEUROSCI.1740-19.2019

PMCID:: PMC6786817

Abstract Article PDF–5.3M

Select item 677415516.

The Lack of Emx2 Causes Impairment ofReelin Signaling and Defects of Neuronal Migration in the Developing Cerebral Cortex

Antonello Mallamaci, Sara Mercurio, Luca Muzio, Chiara Cecchi, Celia Leonor Pardini, Peter Gruss, Edoardo Boncinelli

J Neurosci. 2000 Feb 1; 20(3): 1109–1118. doi: 10.1523/JNEUROSCI.20-03-01109.2000

PMCID:: PMC6774155

Abstract Article PDF–1.1M

Select item 677222817.

Emx2 Is Required for Growth of the Hippocampus But Not for Hippocampal Field Specification

Shubha Tole, Guy Goudreau, Stavroula Assimacopoulos, Elizabeth A. Grove

J Neurosci. 2000 Apr 1; 20(7): 2618–2625. doi: 10.1523/JNEUROSCI.20-07-02618.2000

PMCID:: PMC6772228

Abstract Article PDF–1.6M

Select item 676517918.

Genomic architecture of Shh-dependent cochlear morphogenesis

Victor Muthu, Alex M. Rohacek, Yao Yao, Staci M. Rakowiecki, Alexander S. Brown, Ying-Tao Zhao, James Meyers, Kyoung-Jae Won, Shweta Ramdas, Christopher D. Brown, Kevin A. Peterson, Douglas J. Epstein

Development. 2019 Sep 15; 146(18): dev181339. Published online 2019 Sep 19. doi: 10.1242/dev.181339