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Items: 1 to 20 of 73

1.
A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function
Allyn J. Schoeffler, Andrew P. May, James M. Berger
Nucleic Acids Res. 2010 Nov; 38(21): 7830–7844. Published online 2010 Jul 31. doi: 10.1093/nar/gkq665
PMCID:
PMC2995079
ArticlePDF–19M
2.
ATP control of dynamic P1 ParA–DNA interactions: a key role for the nucleoid in plasmid partition
Anthony G Vecchiarelli, Yong-Woon Han, Xin Tan, Michiyo Mizuuchi, Rodolfo Ghirlando, Christian Biertümpfel, Barbara E Funnell, Kiyoshi Mizuuchi
Mol Microbiol. 2010 Oct; 78(1): 78–91. Published online 2010 Aug 18. doi: 10.1111/j.1365-2958.2010.07314.x
PMCID:
PMC2950902
ArticlePDF–1.0M
3.
Chromosomal Toxin-Antitoxin Systems May Act as Antiaddiction Modules
Manuel Saavedra De Bast, Natacha Mine, Laurence Van Melderen
J Bacteriol. 2008 Jul; 190(13): 4603–4609. Published online 2008 Apr 25. doi: 10.1128/JB.00357-08
PMCID:
PMC2446810
ArticlePDF–341K
4.
Temperature-sensitive suppressor mutations of the Escherichia coli DNA gyrase B protein.
S. J. Blance, N. L. Williams, Z. A. Preston, J. Bishara, M. S. Smyth, A. Maxwell
Protein Sci. 2000 May; 9(5): 1035–1037. doi: 10.1110/ps.9.5.1035
PMCID:
PMC2144630
SummaryPDF–374K
5.
The peptide antibiotic microcin B17 induces double-strand cleavage of DNA mediated by E. coli DNA gyrase.
J L Vizán, C Hernández-Chico, I del Castillo, F Moreno
EMBO J. 1991 Feb; 10(2): 467–476. doi: 10.1002/j.1460-2075.1991.tb07969.x
PMCID:
PMC452668
SummaryPage BrowsePDF–2.1M
6.
Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.
M Gellert, M H O'Dea, T Itoh, J Tomizawa
Proc Natl Acad Sci U S A. 1976 Dec; 73(12): 4474–4478. doi: 10.1073/pnas.73.12.4474
PMCID:
PMC431506
SummaryPage BrowsePDF–983K
7.
DNA gyrase: affinity chromatography on novobiocin-Sepharose and catalytic properties.
W L Staudenbauer, E Orr
Nucleic Acids Res. 1981 Aug 11; 9(15): 3589–3603. doi: 10.1093/nar/9.15.3589
PMCID:
PMC327377
SummaryPage BrowsePDF–1.1M
8.
Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli.
H Yoshida, M Bogaki, M Nakamura, L M Yamanaka, S Nakamura
Antimicrob Agents Chemother. 1991 Aug; 35(8): 1647–1650. doi: 10.1128/aac.35.8.1647
PMCID:
PMC245234
SummaryPage BrowsePDF–701K
9.
Effects of inhibition of the B subunit of DNA gyrase on conjugation in Escherichia coli.
D C Hooper, J S Wolfson, C Tung, K S Souza, M N Swartz
J Bacteriol. 1989 Apr; 171(4): 2235–2237. doi: 10.1128/jb.171.4.2235-2237.1989
PMCID:
PMC209885
SummaryPage BrowsePDF–537K
10.
Mutations causing aminotriazole resistance and temperature sensitivity reside in gyrB, which encodes the B subunit of DNA gyrase.
W M Toone, K E Rudd, J D Friesen
J Bacteriol. 1992 Aug; 174(16): 5479–5481. doi: 10.1128/jb.174.16.5479-5481.1992
PMCID:
PMC206392
SummaryPage BrowsePDF–617K
11.
Active-Site Residues of Escherichia coli DNA Gyrase Required in Coupling ATP Hydrolysis to DNA Supercoiling and Amino Acid Substitutions Leading to Novobiocin Resistance
Christian H. Gross, Jonathan D. Parsons, Trudy H. Grossman, Paul S. Charifson, Steven Bellon, James Jernee, Maureen Dwyer, Stephen P. Chambers, William Markland, Martyn Botfield, Scott A. Raybuck
Antimicrob Agents Chemother. 2003 Mar; 47(3): 1037–1046. doi: 10.1128/AAC.47.3.1037-1046.2003
PMCID:
PMC149296
ArticlePDF–861K
12.
An unusual mechanism for resistance to the antibiotic coumermycin A1.
I del Castillo, J L Vizán, M C Rodríguez-Sáinz, F Moreno
Proc Natl Acad Sci U S A. 1991 Oct 1; 88(19): 8860–8864. doi: 10.1073/pnas.88.19.8860
PMCID:
PMC52610
SummaryPage BrowsePDF–1.2M
13.
Single-molecule dynamics of DNA gyrase in evolutionarily distant bacteria Mycobacterium tuberculosis and Escherichia coli
Cooper J. Galvin, Matthew Hobson, Jonathan Xianglong Meng, Athena Ierokomos, Ivan E. Ivanov, James M. Berger, Zev Bryant
J Biol Chem. 2023 May; 299(5): 103003. Published online 2023 Feb 11. doi: 10.1016/j.jbc.2023.103003
PMCID:
PMC10130225
ArticlePDF–3.1M
14.
Fluoroquinolone-Gyrase-DNA Complexes: TWO MODES OF DRUG BINDING
Arkady Mustaev, Muhammad Malik, Xilin Zhao, Natalia Kurepina, Gan Luan, Lisa M. Oppegard, Hiroshi Hiasa, Kevin R. Marks, Robert J. Kerns, James M. Berger, Karl Drlica
J Biol Chem. 2014 May 2; 289(18): 12300–12312. Published online 2014 Feb 4. doi: 10.1074/jbc.M113.529164
PMCID:
PMC4007428
ArticlePDF–3.0M
15.
Internal Dynamics of Supercoiled DNA Molecules
Thomas Kalkbrenner, Axel Arnold, Sander J. Tans
Biophys J. 2009 Jun 17; 96(12): 4951–4955. doi: 10.1016/j.bpj.2009.03.056
PMCID:
PMC2712042
ArticlePDF–251K
16.
Dynamics of the Trimeric AcrB Transporter Protein Inferred From a B-Factor Analysis of the Crystal Structure
W.C. Lu, C.Z. Wang, E.W. Yu, K.M. Ho
Proteins. Author manuscript; available in PMC 2009 Jul 2.
Published in final edited form as: Proteins. 2006 Jan 1; 62(1): 152–158. doi: 10.1002/prot.20743
PMCID:
PMC2705243
ArticlePDF–2.1M
17.
Bacterial DNA topology and infectious disease
Charles J. Dorman, Colin P. Corcoran
Nucleic Acids Res. 2009 Feb; 37(3): 672–678. Published online 2008 Dec 10. doi: 10.1093/nar/gkn996
PMCID:
PMC2647292
ArticlePDF–122K
18.
Use of Gyrase Resistance Mutants To Guide Selection of 8-Methoxy-Quinazoline-2,4-Diones
Nadezhda German, Muhammad Malik, Jonathan D. Rosen, Karl Drlica, Robert J. Kerns
Antimicrob Agents Chemother. 2008 Nov; 52(11): 3915–3921. Published online 2008 Sep 2. doi: 10.1128/AAC.00330-08
PMCID:
PMC2573108
ArticlePDF–510K
19.
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases
Sara N. Richter, Giulia Giaretta, Valentina Comuzzi, Elisabetta Leo, Lesley A. Mitchenall, L. Mark Fisher, Anthony Maxwell, Manlio Palumbo
Nucleic Acids Res. 2007 Sep; 35(18): 6075–6085. Published online 2007 Aug 30. doi: 10.1093/nar/gkm653
PMCID:
PMC2094056
ArticlePDF–1.0M
20.
Discovery of Novel DNA Gyrase Inhibitors by High-Throughput Virtual Screening
David A. Ostrov, José A. Hernández Prada, Patrick E. Corsino, Kathryn A. Finton, Nhan Le, Thomas C. Rowe
Antimicrob Agents Chemother. 2007 Oct; 51(10): 3688–3698. Published online 2007 Aug 6. doi: 10.1128/AAC.00392-07
PMCID:
PMC2043263
ArticlePDF–831K

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