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Select item 97922011.

A pan-cancer analysis of ring finger protein 135 and its relationship to triple-negative breast cancer proliferation and metastasis

Yiqun Yao, Guanyu Gong, Zijian Guo, Dianlong Zhang

Aging (Albany NY) 2022 Dec 15; 14(23): 9758–9772. Published online 2022 Dec 10. doi: 10.18632/aging.204429

PMCID:: PMC9792201

Article PDF–1.8M

Select item 63694482.

Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting

Caroline F. Wright, Ben West, Marcus Tuke, Samuel E. Jones, Kashyap Patel, Thomas W. Laver, Robin N. Beaumont, Jessica Tyrrell, Andrew R. Wood, Timothy M. Frayling, Andrew T. Hattersley, Michael N. Weedon

Am J Hum Genet. 2019 Feb 7; 104(2): 275–286. Published online 2019 Jan 18. doi: 10.1016/j.ajhg.2018.12.015

PMCID:: PMC6369448

Article PDF–574K

Select item 51675533.

Evidence of Recent Intricate Adaptation in Human Populations

Leeyoung Park

PLoS One. 2016; 11(12): e0165870. Published online 2016 Dec 19. doi: 10.1371/journal.pone.0165870

PMCID:: PMC5167553

Article PDF–4.5M

Select item 47466314.

RNF135, RING finger protein, promotes the proliferation of human glioblastoma cells in vivo and in vitro via the ERK pathway

Yongjian Liu, Feng Wang, Yongsheng Liu, Yiqun Yao, Xiupeng Lv, Bin Dong, Jun Li, Siyang Ren, Yiwen Yao, Yinghui Xu

Sci Rep. 2016; 6: 20642. Published online 2016 Feb 9. doi: 10.1038/srep20642

PMCID:: PMC4746631

Article PDF–2.5M

Select item 107610495.

Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma

Yanteng Zhao, Lei Zhao, Huifang Jin, Ying Xie, Liyinghui Chen, Wei Zhang, Lanlan Dong, Lianglu Zhang, Yue Huang, Kangkang Wan, Qiankun Yang, Shaochi Wang

Epigenetics. 2024; 19(1): 2299044. Published online 2023 Dec 28. doi: 10.1080/15592294.2023.2299044

PMCID:: PMC10761049

Article PDF–4.3M

Select item 94005026.

Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments ZAP-Mediated Restriction of HIV-1

Marlene V. Buckmaster, Stephen P. Goff

J Virol. 2022 Aug; 96(16): e00526-22. Published online 2022 Aug 1. doi: 10.1128/jvi.00526-22

PMCID:: PMC9400502

Article PDF–2.9M

Select item 81041127.

Nonsegmented Negative-Sense RNA Viruses Utilize N⁶-Methyladenosine (m⁶A) as a Common Strategy To Evade Host Innate Immunity

Mijia Lu, Miaoge Xue, Hai-Tao Wang, Elizabeth L. Kairis, Sadeem Ahmad, Jiangbo Wei, Zijie Zhang, Qinzhe Liu, Yuexiu Zhang, Youling Gao, Dominique Garcin, Mark E. Peeples, Amit Sharma, Sun Hur, Chuan He, Jianrong Li

J Virol. 2021 May; 95(9): e01939-20. Prepublished online 2021 Feb 3. Published online 2021 Apr 12. doi: 10.1128/JVI.01939-20

PMCID:: PMC8104112

Article PDF–4.0M

Select item 88274858.

African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity

Yong Ran, Dan Li, Mei-Guang Xiong, Hua-Nan Liu, Tao Feng, Zheng-Wang Shi, Yu-Hui Li, Huang-Ning Wu, Su-Yun Wang, Hai-Xue Zheng, Yan-Yi Wang

PLoS Pathog. 2022 Jan; 18(1): e1010270. Published online 2022 Jan 28. doi: 10.1371/journal.ppat.1010270

PMCID:: PMC8827485

Article PDF–2.3M

Select item 84454859.

Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression

Qi-Xin Hu, Hui-Yi Wang, Lu Jiang, Chen-Yu Wang, Lin-Gao Ju, Yuan Zhu, Bo Zhong, Min Wu, Zhen Wang, Lian-Yun Li

PLoS Pathog. 2021 Sep; 17(9): e1009918. Published online 2021 Sep 16. doi: 10.1371/journal.ppat.1009918

PMCID:: PMC8445485

Article PDF–3.8M

Select item 496794810.

RNF123 has an E3 ligase‐independent function in RIG‐I‐like receptor‐mediated antiviral signaling

Shuai Wang, Yong‐Kang Yang, Tao Chen, Heng Zhang, Wei‐Wei Yang, Sheng‐Sheng Song, Zhong‐He Zhai, Dan‐Ying Chen

EMBO Rep. 2016 Aug; 17(8): 1155–1168. Published online 2016 Jun 16. doi: 10.15252/embr.201541703

PMCID:: PMC4967948

Article PDF–1.7M

Select item 268458811.

REUL Is a Novel E3 Ubiquitin Ligase and Stimulator of Retinoic-Acid-Inducible Gene-I

Dong Gao, Yong-Kang Yang, Rui-Peng Wang, Xiang Zhou, Fei-Ci Diao, Min-Dian Li, Zhong-He Zhai, Zheng-Fan Jiang, Dan-Ying Chen

PLoS One. 2009; 4(6): e5760. Published online 2009 Jun 1. doi: 10.1371/journal.pone.0005760

PMCID:: PMC2684588

Article PDF–1.7M

Select item 541862712.

Ube2D3 and Ube2N are essential for RIG-I-mediated MAVS aggregation in antiviral innate immunity

Yuheng Shi, Bofeng Yuan, Wenting Zhu, Rui Zhang, Lin Li, Xiaojing Hao, She Chen, Fajian Hou

Nat Commun. 2017; 8: 15138. Published online 2017 May 4. doi: 10.1038/ncomms15138

PMCID:: PMC5418627

Article PDF–2.0M

Select item 652504713.

Ubiquitin-dependent and -independent roles of E3 ligase RIPLET in innate immunity

Cristhian Cadena, Sadeem Ahmad, Audrey Xavier, Joschka Willemsen, Sehoon Park, Ji Woo Park, Seong-Wook Oh, Takashi Fujita, Fajian Hou, Marco Binder, Sun Hur

Cell. Author manuscript; available in PMC 2020 May 16.

Published in final edited form as: Cell. 2019 May 16; 177(5): 1187–1200.e16. Published online 2019 Apr 18. doi: 10.1016/j.cell.2019.03.017

PMCID:: PMC6525047

Article PDF–2.2M

Select item 818367614.

Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases

Kazuki Kato, Sadeem Ahmad, Zixiang Zhu, Janet M. Young, Xin Mu, Sehoon Park, Harmit S. Malik, Sun Hur

Mol Cell. Author manuscript; available in PMC 2021 Jun 7.

Published in final edited form as: Mol Cell. 2021 Feb 4; 81(3): 599–613.e8. Published online 2020 Dec 28. doi: 10.1016/j.molcel.2020.11.047

PMCID:: PMC8183676

Article PDF–3.6M

Select item 123548215.

Molecular Characterization and Gene Content of Breakpoint Boundaries in Patients with Neurofibromatosis Type 1 with 17q11.2 Microdeletions

Dieter E. Jenne, Sigrid Tinschert, Heike Reimann, Wolfgang Lasinger, Gundula Thiel, Horst Hameister, Hildegard Kehrer-Sawatzki

Am J Hum Genet. 2001 Sep; 69(3): 516–527. Published online 2001 Jul 20. doi: 10.1086/323043

PMCID:: PMC1235482

Article PDF–679K

Select item 373849216.

A Distinct Role of Riplet-Mediated K63-Linked Polyubiquitination of the RIG-I Repressor Domain in Human Antiviral Innate Immune Responses

Hiroyuki Oshiumi, Moeko Miyashita, Misako Matsumoto, Tsukasa Seya

PLoS Pathog. 2013 Aug; 9(8): e1003533. Published online 2013 Aug 8. doi: 10.1371/journal.ppat.1003533

PMCID:: PMC3738492

Article PDF–3.8M

Select item 289479017.

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature

Jianhua Zhao, Mingyao Li, Jonathan P Bradfield, Haitao Zhang, Frank D Mentch, Kai Wang, Patrick M Sleiman, Cecilia E Kim, Joseph T Glessner, Cuiping Hou, Brendan J Keating, Kelly A Thomas, Maria L Garris, Sandra Deliard, Edward C Frackelton, F George Otieno, Rosetta M Chiavacci, Robert I Berkowitz, Hakon Hakonarson, Struan FA Grant

BMC Med Genet. 2010; 11: 96. Published online 2010 Jun 14. doi: 10.1186/1471-2350-11-96

PMCID:: PMC2894790

Article PDF–803K

Select item 791045918.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Article PDF–3.3M

Select item 553358519.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Article PDF–5.9M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Article PDF–3.1M

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