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Select item 58161901.

Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch

Di Feng, Jacob Notbohm, Ava Benjamin, Shijie He, Minxian Wang, Lay-Hong Ang, Minaspi Bantawa, Mehdi Bouzid, Emanuela Del Gado, Ramaswamy Krishnan, Martin R. Pollak

Proc Natl Acad Sci U S A. 2018 Feb 13; 115(7): 1517–1522. Published online 2018 Jan 29. doi: 10.1073/pnas.1717870115

PMCID:: PMC5816190

Article PDF–1.2M

Select item 42454602.

Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo

Ivica Grgic, Andreas F. Hofmeister, Giulio Genovese, Andrea J. Bernhardy, Hua Sun, Omar H. Maarouf, Vanesa Bijol, Martin R. Pollak, Benjamin D. Humphreys

Kidney Int. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Kidney Int. 2014 Dec; 86(6): 1116–1129. Published online 2014 Jun 18. doi: 10.1038/ki.2014.204

PMCID:: PMC4245460

Article PDF–1.9M

Select item 29808423.

Mice with altered α-actinin-4 expression have distinct morphologic patterns of glomerular disease

Joel M. Henderson, Salah al-Waheeb, Astrid Weins, Savita V. Dandapani, Martin R. Pollak

Kidney Int. Author manuscript; available in PMC 2010 Nov 14.

Published in final edited form as: Kidney Int. 2008 Mar; 73(6): 741–750. Published online 2008 Jan 9. doi: 10.1038/sj.ki.5002751

PMCID:: PMC2980842

Article PDF–1.7M

Select item 29786804.

α-Actinin-4 Is Essential for Maintaining the Spreading, Motility and Contractility of Fibroblasts

Hanshuang Shao, James H.-C. Wang, Martin R. Pollak, Alan Wells

PLoS One. 2010; 5(11): e13921. Published online 2010 Nov 11. doi: 10.1371/journal.pone.0013921

PMCID:: PMC2978680

Article PDF–1.5M

Select item 4231415.

α-Actinin-4-Mediated FSGS: An Inherited Kidney Disease Caused by an Aggregated and Rapidly Degraded Cytoskeletal Protein

June Yao, Tu Cam Le, Claudine H Kos, Joel M Henderson, Phillip G Allen, Bradley M Denker, Martin R Pollak

PLoS Biol. 2004 Jun; 2(6): e167. Published online 2004 Jun 15. doi: 10.1371/journal.pbio.0020167

PMCID:: PMC423141

Article PDF–402K

Select item 73510026.

Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis

Di Feng, Mukesh Kumar, Jan Muntel, Susan B. Gurley, Gabriel Birrane, Isaac E. Stillman, Lai Ding, Minxian Wang, Saima Ahmed, Johannes Schlondorff, Seth L. Alper, Tom Ferrante, Susan L. Marquez, Carlos F. Ng, Richard Novak, Donald E. Ingber, Hanno Steen, Martin R. Pollak

J Am Soc Nephrol. 2020 Jul; 31(7): 1479–1495. Published online 2020 Jun 15. doi: 10.1681/ASN.2019101032

PMCID:: PMC7351002

Article

Select item 39310577.

Small Leucine Zipper Protein (sLZIP) Negatively Regulates Skeletal Muscle Differentiation via Interaction with α-Actinin-4

Hyoung-Tae An, Jeonghan Kim, Seungmin Yoo, Jesang Ko

J Biol Chem. 2014 Feb 21; 289(8): 4969–4979. Published online 2013 Dec 29. doi: 10.1074/jbc.M113.515395

PMCID:: PMC3931057

Article PDF–2.7M

Select item 20421658.

Disease-associated mutant α-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity

Astrid Weins, Johannes S. Schlondorff, Fumihiko Nakamura, Bradley M. Denker, John H. Hartwig, Thomas P. Stossel, Martin R. Pollak

Proc Natl Acad Sci U S A. 2007 Oct 9; 104(41): 16080–16085. Published online 2007 Sep 27. doi: 10.1073/pnas.0702451104

PMCID:: PMC2042165

Article PDF–1.2M

Select item 94686039.

α-Actinin-4 recruits Shp2 into focal adhesions to potentiate ROCK2 activation in podocytes

Chien-Chun Tseng, Ru-Hsuan Zheng, Ting-Wei Lin, Chih-Chiang Chou, Yu-Chia Shih, Shao-Wei Liang, Hsiao-Hui Lee

Life Sci Alliance. 2022 Nov; 5(11): e202201557. Published online 2022 Sep 12. doi: 10.26508/lsa.202201557

PMCID:: PMC9468603

Article PDF–3.0M

Select item 769953610.

ACTN4 Mediates SEPT14 Mutation-Induced Sperm Head Defects

Yu-Hua Lin, Chia-Yen Huang, Chih-Chun Ke, Ya-Yun Wang, Tsung-Hsuan Lai, Hsuan-Che Liu, Wei-Chi Ku, Chying-Chyuan Chan, Ying-Hung Lin

Biomedicines. 2020 Nov; 8(11): 518. Published online 2020 Nov 19. doi: 10.3390/biomedicines8110518

PMCID:: PMC7699536

Article PDF–3.8M

Select item 363368911.

The Carboxyl Tail of Alpha-Actinin-4 Regulates Its Susceptibility to m-Calpain and thus Functions in Cell Migration and Spreading

Hanshuang Shao, Tim Travers, Carlos Camacho, Alan Wells

Int J Biochem Cell Biol. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Int J Biochem Cell Biol. 2013 Jun; 45(6): 1051–1063. Published online 2013 Mar 1. doi: 10.1016/j.biocel.2013.02.015

PMCID:: PMC3633689

Article PDF–5.2M

Select item 362529112.

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation

Pere Roca-Cusachs, Armando del Rio, Eileen Puklin-Faucher, Nils C. Gauthier, Nicolas Biais, Michael P. Sheetz

Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15): E1361–E1370. Published online 2013 Mar 20. doi: 10.1073/pnas.1220723110

PMCID:: PMC3625291

Article PDF–2.0M

Select item 242314513.

Involvement of Actinin-4 in the Recruitment of JRAB/MICAL-L2 to Cell-Cell Junctions and the Formation of Functional Tight Junctions

Hiroyoshi Nakatsuji, Noriyuki Nishimura, Rie Yamamura, Hiro-omi Kanayama, Takuya Sasaki

Mol Cell Biol. 2008 May; 28(10): 3324–3335. Published online 2008 Mar 10. doi: 10.1128/MCB.00144-08

PMCID:: PMC2423145

Article PDF–1.6M

Select item 911430314.

Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear

Mark A. Rudolf, Anna Andreeva, Christina E. Kim, Anthony C.-J. DeNovio, Antoan N. Koshar, Wendy Baker, Alexander X. Cartagena-Rivera, Jeffrey T. Corwin

Front Cell Neurosci. 2022; 16: 859882. Published online 2022 May 4. doi: 10.3389/fncel.2022.859882