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Select item 53402511.

Regulatory landscape and clinical implication of MBD3 in human malignant glioma

Yi Cui, Jian Li, Ling Weng, Sara E. Wirbisky, Jennifer L. Freeman, Jingping Liu, Qing Liu, Xianrui Yuan, Joseph Irudayaraj

Oncotarget. 2016 Dec 6; 7(49): 81698–81714. Published online 2016 Nov 7. doi: 10.18632/oncotarget.13173

PMCID:: PMC5340251

Article PDF–12M

Select item 52201562.

Methyl-CpG-binding domain 3 inhibits epithelial–mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling

Min Xu, Junbo He, Jie Li, Wen Feng, Hailang Zhou, Hong Wei, Meng Zhou, Ying Lu, Jian Zeng, Wanxin Peng, Fengyi Du, Aihua Gong

Br J Cancer. 2017 Jan 3; 116(1): 91–99. Published online 2016 Nov 29. doi: 10.1038/bjc.2016.397

PMCID:: PMC5220156

Article PDF–2.4M

Select item 43810563.

Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy

Yi Cui, Joseph Irudayaraj

Nucleic Acids Res. 2015 Mar 31; 43(6): 3046–3055. Published online 2015 Mar 9. doi: 10.1093/nar/gkv098

PMCID:: PMC4381056

Article PDF–1.9M

Select item 38732314.

MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes

Takashi Shimbo, Ying Du, Sara A. Grimm, Archana Dhasarathy, Deepak Mav, Ruchir R. Shah, Huidong Shi, Paul A. Wade

PLoS Genet. 2013 Dec; 9(12): e1004028. Published online 2013 Dec 26. doi: 10.1371/journal.pgen.1004028

PMCID:: PMC3873231

Article PDF–2.0M

Select item 19514835.

Epigenetic Programming of the rRNA Promoter by MBD3

Shelley E. Brown, Moshe Szyf

Mol Cell Biol. 2007 Jul; 27(13): 4938–4952. Published online 2007 Apr 23. doi: 10.1128/MCB.01880-06

Correction in:: Mol Cell Biol. 2008 Feb; 28(3): 1195.

PMCID:: PMC1951483

Article PDF–987K

Select item 95200266.

Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3

Gage O. Leighton, Elizabeth Marie Irvin, Parminder Kaur, Ming Liu, Changjiang You, Dhruv Bhattaram, Jacob Piehler, Robert Riehn, Hong Wang, Hai Pan, David C. Williams, Jr.

J Biol Chem. 2022 Oct; 298(10): 102428. Published online 2022 Aug 28. doi: 10.1016/j.jbc.2022.102428

PMCID:: PMC9520026

Article PDF–3.6M

Select item 93815937.

MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2

Weiwei Yan, Qiuying Han, Lin Gong, Xiaoyan Zhan, Wanjin Li, Zenglin Guo, Jiangman Zhao, Tingting Li, Zhaofang Bai, Jin Wu, Yan Huang, Luye Lv, Haixin Zhao, Hong Cai, Shaoyi Huang, Xinwei Diao, Yuan Chen, Weili Gong, Qing Xia, Jianghong Man, Liang Chen, Guanghai Dai, Tao Zhou

Br J Cancer. 2022 Sep 1; 127(4): 612–623. Published online 2022 Apr 30. doi: 10.1038/s41416-022-01831-5

PMCID:: PMC9381593

Article PDF–4.3M

Select item 72019228.

Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation

Xiaoyan Zhan, Saisai Guo, Yuanyuan Li, Haowen Ran, Haohao Huang, Lanjuan Mi, Jin Wu, Xinzheng Wang, Dake Xiao, Lishu Chen, Da Li, Songyang Zhang, Xu Yan, Yu Yu, Tingting Li, Qiuying Han, Kun He, Jiuwei Cui, Tao Li, Tao Zhou, Jeremy N. Rich, Shideng Bao, Xuemin Zhang, Ailing Li, Jianghong Man

J Exp Med. 2020 May 4; 217(5): e20191340. Published online 2020 Mar 17. doi: 10.1084/jem.20191340

PMCID:: PMC7201922

Article PDF–9.6M

Select item 62945679.

The C-terminal D/E-rich domain of MBD3 is a putative Z-DNA mimic that competes for Zα DNA-binding activity

Chi-Hua Lee, Yan-Ping Shih, Meng-Ru Ho, Andrew H-J Wang

Nucleic Acids Res. 2018 Dec 14; 46(22): 11806–11821. Published online 2018 Oct 10. doi: 10.1093/nar/gky933

PMCID:: PMC6294567

Article PDF–7.5M

Select item 535161310.

MBD3 inhibits formation of liver cancer stem cells

Ruizhi Li, Qihua He, Shuo Han, Mingzhi Zhang, Jinwen Liu, Ming Su, Shiruo Wei, Xuan Wang, Li Shen

Oncotarget. 2017 Jan 24; 8(4): 6067–6078. Published online 2016 Nov 22. doi: 10.18632/oncotarget.13496

PMCID:: PMC5351613

Article PDF–7.8M

Select item 359769711.

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences

Katharina Günther, Mareike Rust, Joerg Leers, Thomas Boettger, Maren Scharfe, Michael Jarek, Marek Bartkuhn, Rainer Renkawitz

Nucleic Acids Res. 2013 Mar; 41(5): 3010–3021. Published online 2013 Jan 29. doi: 10.1093/nar/gkt035

PMCID:: PMC3597697

Article PDF–2.9M

Select item 294806412.

Phosphorylated P68 RNA Helicase Activates Snail1 Transcription by Promoting HDAC1 Dissociation from the Snail1 Promoter

Christie L. Carter, Chunru Lin, Chia-yi Liu, Liuqing Yang, Zhi-Ren Liu

Oncogene. Author manuscript; available in PMC 2011 Mar 30.

Published in final edited form as: Oncogene. 2010 Sep 30; 29(39): 5427–5436. Published online 2010 Aug 2. doi: 10.1038/onc.2010.276

PMCID:: PMC2948064

Article PDF–1.0M

Select item 828886613.

MKRN3 regulates the epigenetic switch of mammalian puberty via ubiquitination of MBD3

Chuanyin Li, Wenli Lu, Liguang Yang, Zhengwei Li, Xiaoyi Zhou, Rong Guo, Junqi Wang, Zhebao Wu, Zhiya Dong, Guang Ning, Yujiang Shi, Yinmin Gu, Peng Chen, Zijian Hao, Tianting Han, Meiqiang Yang, Wei Wang, Xuehui Huang, Yixue Li, Shan Gao, Ronggui Hu

Natl Sci Rev. 2020 Mar; 7(3): 671–685. Published online 2020 Feb 14. doi: 10.1093/nsr/nwaa023

PMCID:: PMC8288866

Article PDF–2.2M

Select item 356156014.

Unique Features of the Anti-parallel, Heterodimeric Coiled-coil Interaction between Methyl-cytosine Binding Domain 2 (MBD2) Homologues and GATA Zinc Finger Domain Containing 2A (GATAD2A/p66α)

Ninad M. Walavalkar, Nathaniel Gordon, David C. Williams, Jr.

J Biol Chem. 2013 Feb 1; 288(5): 3419–3427. Published online 2012 Dec 13. doi: 10.1074/jbc.M112.431346

PMCID:: PMC3561560

Article PDF–2.0M

Select item 325282115.

Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells

Ozlem Yildirim, Ruowang Li, Jui-Hung Hung, Poshen B. Chen, Xianjun Dong, Ly-sha Ee, Zhiping Weng, Oliver J. Rando, Thomas G. Fazzio

Cell. Author manuscript; available in PMC 2012 Dec 23.

Published in final edited form as: Cell. 2011 Dec 23; 147(7): 1498–1510. doi: 10.1016/j.cell.2011.11.054

PMCID:: PMC3252821

Article PDF–3.9M

Select item 254699816.

MBD3, a Component of the NuRD Complex, Facilitates Chromatin Alteration and Deposition of Epigenetic Marks

Lluis Morey, Carmen Brenner, Francesco Fazi, Raffaella Villa, Arantxa Gutierrez, Marcus Buschbeck, Clara Nervi, Saverio Minucci, Francois Fuks, Luciano Di Croce

Mol Cell Biol. 2008 Oct; 28(19): 5912–5923. Published online 2008 Jul 21. doi: 10.1128/MCB.00467-08