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Items: 1 to 20 of 83

1.
Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems
Ali Reza Noori, Elaheh Sadat Hosseini, Maryam Nikkhah, Saman Hosseinkhani
Arch Biochem Biophys. 2018 Mar 15; 642: 46–51. doi: 10.1016/j.abb.2018.01.017
PMCID:
PMC5856089
Article
2.
Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas
Jayshree L. Hirpara, Thomas Loh, Siok Bian Ng, Wee Joo Chng, Shazib Pervaiz
Oncotarget. 2016 Dec 20; 7(51): 83964–83975. Published online 2016 Nov 14. doi: 10.18632/oncotarget.13336
PMCID:
PMC5356638
ArticlePDF–4.9M
3.
Modeling of interaction between cytochrome c and the WD domains of Apaf-1: bifurcated salt bridges underlying apoptosome assembly
Daria N. Shalaeva, Daria V. Dibrova, Michael Y. Galperin, Armen Y. Mulkidjanian
Biol Direct. 2015; 10: 29. Published online 2015 May 27. doi: 10.1186/s13062-015-0059-4
PMCID:
PMC4445527
ArticlePDF–2.7M
4.
Rationales for expression and altered expression of apoptotic protease activating factor-1 gene in gastric cancer
He-Ling Wang, Han Bai, Yan Li, Jun Sun, Xue-Qing Wang
World J Gastroenterol. 2007 Oct 14; 13(38): 5060–5064. Published online 2007 Oct 14. doi: 10.3748/wjg.v13.i38.5060
PMCID:
PMC4434634
ArticlePDF–1.0M
5.
High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome
Shucheng Gu, Youshan Zhao, Juan Guo, Feng Xu, Chengming Fei, Xi Zhang, Chao Xiao, Chunkang Chang, Xiao Li
Tumour Biol. 2014 Mar; 35(3): 2211–2218. Published online 2013 Oct 19. doi: 10.1007/s13277-013-1294-x
PMCID:
PMC3967075
ArticlePDF–679K
6.
Modulating Roles of Amiloride in Irradiation-Induced Antiproliferative Effects in Glioblastoma Multiforme Cells Involving Akt Phosphorylation and the Alternative Splicing of Apoptotic Genes
Jen-Yang Tang, Hsueh-Wei Chang, Jan-Gowth Chang
DNA Cell Biol. 2013 Sep; 32(9): 504–510. doi: 10.1089/dna.2013.1998
PMCID:
PMC3752517
ArticlePDF–362K
7.
Changes in Apaf-1 conformation that drive apoptosome assembly
Shujun Yuan, Maya Topf, Thomas F. Reubold, Susanne Eschenburg, Christopher W. Akey
Biochemistry. Author manuscript; available in PMC 2014 Apr 2.
Published in final edited form as: Biochemistry. 2013 Apr 2; 52(13): 2319–2327. Published online 2013 Mar 22. doi: 10.1021/bi301721g
PMCID:
PMC3645920
ArticlePDF–8.4M
8.
A Sequencing-Based Survey of Functional APAF1 Alleles in a Large Sample of Individuals with Affective Illness and Population Controls
Zenab Amin, Katarzyna Kanarek, Evgeny Krupitsky, Espen Walderhaug, Risto Ilomäki, Hilary Blumberg, Lawrence H. Price, Zubin Bhagwagar, Linda L. Carpenter, Audrey R. Tyrka, Andres Magnusson, Nils Inge Landrø, Edwin Zvartau, Joel Gelernter, C. Neill Epperson, Pirkko Räsänen, Jari Siironen, Jaakko Lappalainen
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2013 Feb 24.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5; 153B(1): 332–335. doi: 10.1002/ajmg.b.30984
PMCID:
PMC3580167
ArticlePDF–284K
9.
A New Model for the Transition of APAF-1 from Inactive Monomer to Caspase-activating Apoptosome
Thomas F. Reubold, Sabine Wohlgemuth, Susanne Eschenburg
J Biol Chem. 2009 Nov 20; 284(47): 32717–32724. Published online 2009 Sep 30. doi: 10.1074/jbc.M109.014027
PMCID:
PMC2781688
ArticlePDF–1.3M
10.
Reduced Apaf-1 expression in human cutaneous melanomas
D L Dai, M Martinka, J A Bush, G Li
Br J Cancer. 2004 Sep 13; 91(6): 1089–1095. Published online 2004 Aug 10. doi: 10.1038/sj.bjc.6602092
PMCID:
PMC2747705
ArticlePDF–182K
11.
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer
F Christoph, C Kempkensteffen, S Weikert, J Köllermann, H Krause, K Miller, M Schostak, M Schrader
Br J Cancer. 2006 Dec 18; 95(12): 1701–1707. Published online 2006 Nov 28. doi: 10.1038/sj.bjc.6603482
PMCID:
PMC2360762
ArticlePDF–114K
12.
The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c
Brona M. Murphy, Amanda J. O'Neill, Colin Adrain, R. William G. Watson, Seamus J. Martin
J Exp Med. 2003 Mar 3; 197(5): 625–632. doi: 10.1084/jem.20021862
PMCID:
PMC2193828
ArticlePDF–319K
13.
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.
Y Hu, M A Benedict, L Ding, G Núñez
EMBO J. 1999 Jul 1; 18(13): 3586–3595. doi: 10.1093/emboj/18.13.3586
PMCID:
PMC1171437
SummaryPDF–290K
14.
Upregulation of APAF1 and CSF1R in Peripheral Blood Mononuclear Cells of Parkinson’s Disease
Kuo-Hsuan Chang, Chia-Hsin Liu, Yi-Ru Wang, Yen-Shi Lo, Chun-Wei Chang, Hsiu-Chuan Wu, Chiung-Mei Chen
Int J Mol Sci. 2023 Apr; 24(8): 7095. Published online 2023 Apr 12. doi: 10.3390/ijms24087095
PMCID:
PMC10139006
ArticlePDF–621K
15.
APAF1‐Binding Long Noncoding RNA Promotes Tumor Growth and Multidrug Resistance in Gastric Cancer by Blocking Apoptosome Assembly
Qiang Wang, Chen Chen, Xiao Xu, Chuanjun Shu, Changchang Cao, Zhangding Wang, Yao Fu, Lei Xu, Kaiyue Xu, Jiawen Xu, Anliang Xia, Bo Wang, Guifang Xu, Xiaoping Zou, Ruibao Su, Wei Kang, Yuanchao Xue, Ran Mo, Beicheng Sun, Shouyu Wang
Adv Sci (Weinh) 2022 Oct; 9(28): 2201889. Published online 2022 Aug 17. doi: 10.1002/advs.202201889
PMCID:
PMC9534967
ArticlePDF–10M
16.
Exosomal microRNA⁃93⁃3p secreted by bone marrow mesenchymal stem cells downregulates apoptotic peptidase activating factor 1 to promote wound healing
Caiqi Shen, Changbo Tao, Aijun Zhang, Xueyang Li, Yanping Guo, Hanxiao Wei, Qichuan Yin, Qiang Li, Peisheng Jin
Bioengineered. 2022; 13(1): 27–37. Published online 2021 Dec 24. doi: 10.1080/21655979.2021.1997077
PMCID:
PMC8805970
ArticlePDF–3.0M
17.
Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis
Ronald Jemmerson, Katherine Staskus, LeeAnn Higgins, Kathleen Conklin, Ameeta Kelekar
Apoptosis. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Apoptosis. 2021 Feb; 26(1-2): 71–82. Published online 2021 Jan 1. doi: 10.1007/s10495-020-01647-9
PMCID:
PMC7904597
ArticlePDF–1.6M
18.
Hypoxia-induced up-regulation of miR-27a promotes paclitaxel resistance in ovarian cancer
Lanlan Feng, Fangrong Shen, Jinhua Zhou, Yan Li, Rong Jiang, Youguo Chen
Biosci Rep. 2020 Apr 30; 40(4): BSR20192457. Published online 2020 Mar 31. doi: 10.1042/BSR20192457
PMCID:
PMC7109003
ArticlePDF–1.4M
19.
Circular RNA Cdr1as sensitizes bladder cancer to cisplatin by upregulating APAF1 expression through miR‐1270 inhibition
Wenbo Yuan, Rui Zhou, Jingzi Wang, Jie Han, Xiao Yang, Hao Yu, Hongcheng Lu, Xiaolei Zhang, Pengchao Li, Jun Tao, Jifu Wei, Qiang Lu, Haiwei Yang, Min Gu
Mol Oncol. 2019 Jul; 13(7): 1559–1576. Published online 2019 Jun 9. doi: 10.1002/1878-0261.12523
PMCID:
PMC6599840
ArticlePDF–3.1M
20.
Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects
Catherine J. Spellicy, Joy Norris, Renee Bend, Caleb Bupp, Paul Mester, Tracy Reynolds, Jane Dean, Yunhui Peng, Emil Alexov, Charles E. Schwartz, Roger S. Stevenson, Michael J. Friez
Eur J Hum Genet. 2018 Mar; 26(3): 420–427. Published online 2018 Jan 22. doi: 10.1038/s41431-017-0025-y
PMCID:
PMC5838979
ArticlePDF–1.1M

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