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Select item 84348001.

Induction of the endogenous sialoglycan ligand for eosinophil death receptor Siglec-8 in chronic rhinosinusitis with hyperplastic nasal polyposis

Hyun Sil Lee, Anabel Gonzalez-Gil, Virginia Drake, T August Li, Ronald L Schnaar, Jean Kim

Glycobiology. 2021 Aug; 31(8): 1026–1036. Published online 2021 Mar 20. doi: 10.1093/glycob/cwab018

PMCID:: PMC8434800

Article PDF–806K

Select item 79227942.

First Evidence for a Role of Siglec-8 in Breast Cancer

Anna Trebo, Nina Ditsch, Tom Degenhardt, Christina Kuhn, Martina Rahmeh, Elisa Schmoeckel, Doris Mayr, Bastian Czogalla, Thomas Kolben, Sarah Meister, Sven Mahner, Udo Jeschke, Anna Hester

Int J Mol Sci. 2021 Feb; 22(4): 2000. Published online 2021 Feb 18. doi: 10.3390/ijms22042000

PMCID:: PMC7922794

Article PDF–3.1M

Select item 65564243.

Siglec-8 in eosinophilic disorders: receptor expression and targeting using chimeric antibodies

Fanny Legrand, Yun Cao, Joshua Wechsler, Xiang Zhu, Nives Zimmermann, Shakuntala Rampertaap, Joseph Monsale, Kimberly Romito, Bradford A. Youngblood, Emily C. Brock, Michelle Makiya, Nenad Tomasevic, Christopher Bebbington, Irina Maric, Dean D. Metcalfe, Bruce S. Bochner, Amy D. Klion

J Allergy Clin Immunol. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: J Allergy Clin Immunol. 2019 Jun; 143(6): 2227–2237.e10. Published online 2018 Dec 10. doi: 10.1016/j.jaci.2018.10.066

PMCID:: PMC6556424

Article PDF–2.4M

Select item 64456444.

Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells

Jeremy A. O’Sullivan, Daniela J. Carroll, Yun Cao, Adriano N. Salicru, Bruce S. Bochner

J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Apr 2.

Published in final edited form as: J Allergy Clin Immunol. 2018 May; 141(5): 1774–1785.e7. Published online 2017 Jul 20. doi: 10.1016/j.jaci.2017.06.028

PMCID:: PMC6445644

Article PDF–1.8M

Select item 58399295.

Siglec-8 is an activating receptor mediating ß2 integrin-dependent function in human eosinophils

Daniela J. Carroll, Jeremy A. O’Sullivan, David B. Nix, Yun Cao, Michael Tiemeyer, Bruce S. Bochner

J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: J Allergy Clin Immunol. 2018 Jun; 141(6): 2196–2207. Published online 2017 Sep 6. doi: 10.1016/j.jaci.2017.08.013

PMCID:: PMC5839929

Article PDF–1.5M

Select item 34118566.

Biomarkers of Eosinophil Involvement in Allergic and Eosinophilic Diseases: review of phenotypic and serum markers including a novel assay to quantify levels of soluble Siglec-8

Ho Jeong Na, Robert G. Hamilton, Amy D. Klion, Bruce S. Bochner

J Immunol Methods. Author manuscript; available in PMC 2013 Sep 28.

Published in final edited form as: J Immunol Methods. 2012 Sep 28; 383(1-2): 39–46. Published online 2012 Jun 6. doi: 10.1016/j.jim.2012.05.017

PMCID:: PMC3411856

Article PDF–1.0M

Select item 33298707.

Developmental, Malignancy-Related, and Cross-Species Analysis of Eosinophil, Mast Cell, and Basophil Siglec-8 Expression

Sherry A. Hudson, Harald Herrmann, Jian Du, Paul Cox, El-Bdaoui Haddad, Barbara Butler, Paul R. Crocker, Steven J. Ackerman, Peter Valent, Bruce S. Bochner

J Clin Immunol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: J Clin Immunol. 2011 Dec; 31(6): 1045–1053. Published online 2011 Sep 22. doi: 10.1007/s10875-011-9589-4

PMCID:: PMC3329870

Article PDF–2.2M

Select item 29873488.

Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma

Pei-Song Gao, Kenichi Shimizu, Audrey V Grant, Nicholas Rafaels, Lin-Fu Zhou, Sherry A Hudson, Satoshi Konno, Nives Zimmermann, Maria I Araujo, Eduardo V Ponte, Alvaro A Cruz, Masaharu Nishimura, Song-Nan Su, Nobuyuki Hizawa, Terry H Beaty, Rasika A Mathias, Marc E Rothenberg, Kathleen C Barnes, Bruce S Bochner

Eur J Hum Genet. 2010 Jun; 18(6): 713–719. Published online 2010 Jan 20. doi: 10.1038/ejhg.2009.239

PMCID:: PMC2987348

Article PDF–458K

Select item 27130939.

Eosinophil-Selective Binding and Proapoptotic Effect in Vitro of a Synthetic Siglec-8 Ligand, Polymeric 6′-Sulfated Sialyl Lewis X

Sherry A. Hudson, Nicolai V. Bovin, Ronald L. Schnaar, Paul R. Crocker, Bruce S. Bochner

J Pharmacol Exp Ther. 2009 Aug; 330(2): 608–612. Published online 2009 May 19. doi: 10.1124/jpet.109.152439

PMCID:: PMC2713093

Article PDF–157K

Select item 481104010.

Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression

Robert P. Schleimer, Ronald L. Schnaar, Bruce S. Bochner

Curr Opin Allergy Clin Immunol. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Curr Opin Allergy Clin Immunol. 2016 Feb; 16(1): 24–30. doi: 10.1097/ACI.0000000000000234

PMCID:: PMC4811040

Article PDF–344K

Select item 435558011.

Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells

Yi Jia, Huifeng Yu, Steve M. Fernandes, Yadong Wei, Anabel Gonzalez-Gil, Mary G. Motari, Katarina Vajn, Whitney W. Stevens, Anju T. Peters, Bruce S. Bochner, Robert C. Kern, Robert P. Schleimer, Ronald L. Schnaar

J Allergy Clin Immunol. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: J Allergy Clin Immunol. 2015 Mar; 135(3): 799–810.e7. doi: 10.1016/j.jaci.2015.01.004

PMCID:: PMC4355580

Article PDF–2.3M

Select item 328230112.

IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils

Ho Jeong Na, Sherry A. Hudson, Bruce S. Bochner

Cytokine. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Cytokine. 2012 Jan; 57(1): 169–174. Published online 2011 Nov 12. doi: 10.1016/j.cyto.2011.10.007

PMCID:: PMC3282301

Article PDF–868K

Select item 274262213.

Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors

Bruce S. Bochner

Clin Exp Allergy. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: Clin Exp Allergy. 2009 Mar; 39(3): 317–324. doi: 10.1111/j.1365-2222.2008.03173.x

PMCID:: PMC2742622

Article PDF–152K

Select item 217612814.

Interleukin-5 Priming of Human Eosinophils Alters Siglec-8–Mediated Apoptosis Pathways

Esra Nutku-Bilir, Sherry A. Hudson, Bruce S. Bochner

Am J Respir Cell Mol Biol. 2008 Jan; 38(1): 121–124. Published online 2007 Aug 9. doi: 10.1165/rcmb.2007-0154OC

PMCID:: PMC2176128

Article PDF–133K

Select item 404206115.

Mechanism of Siglec-8-mediated Cell Death in IL-5-activated Eosinophils: Role for ROS-enhanced MEK/ERK Activation

Gen Kano, Maha Almanan, Bruce S. Bochner, Nives Zimmermann

J Allergy Clin Immunol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: J Allergy Clin Immunol. 2013 Aug; 132(2): 437–445. Published online 2013 May 16. doi: 10.1016/j.jaci.2013.03.024

PMCID:: PMC4042061

Article PDF–1.3M

Select item 122176216.

Identification, characterization and leucocyte expression of Siglec-10, a novel human sialic acid-binding receptor.

J Munday, S Kerr, J Ni, A L Cornish, J Q Zhang, G Nicoll, H Floyd, M G Mattei, P Moore, D Liu, P R Crocker

Biochem J. 2001 Apr 15; 355(Pt 2): 489–497. doi: 10.1042/0264-6021:3550489

PMCID:: PMC1221762

Summary PDF–415K

Select item 51531617.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Article PDF–181K

Select item 135612918.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Article PDF–438K

Select item 52892819.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Article PDF–140K

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Article PDF–118K

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