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Select item 88033381.

Numb and Numblike regulate sarcomere assembly and maintenance

Baolei Wang, Min Yang, Shujuan Li

J Clin Invest. 2022 Feb 1; 132(3): e139420. Published online 2022 Feb 1. doi: 10.1172/JCI139420

Correction in:: J Clin Invest. 2022 Jul 15; 132(14): e162883.

PMCID:: PMC8803338

Article PDF–12M

Select item 81877922.

Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway

Alessandro Ianni, Michael Hofmann, Poonam Kumari, Shahriar Tarighi, Hamza M Al-Tamari, André Görgens, Bernd Giebel, Hendrik Nolte, Marcus Krüger, Isabelle Salwig, Soni Savai Pullamsetti, Andreas Günther, André Schneider, Thomas Braun

Front Cell Dev Biol. 2021; 9: 639162. Published online 2021 May 26. doi: 10.3389/fcell.2021.639162

PMCID:: PMC8187792

Article PDF–9.4M

Select item 67685623.

EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation

Khadar Abdi, Gabriel Neves, Joon Pyun, Emre Kiziltug, Angelica Ahrens, Chay T. Kuo

Cell Rep. Author manuscript; available in PMC 2019 Sep 30.

Published in final edited form as: Cell Rep. 2019 Aug 20; 28(8): 2012–2022.e4. doi: 10.1016/j.celrep.2019.07.056

PMCID:: PMC6768562

Article PDF–2.2M

Select item 33725294.

MiR-34a Represses Numbl in Murine Neural Progenitor Cells and Antagonizes Neuronal Differentiation

Sarah K. Fineberg, Poppy Datta, Colleen S. Stein, Beverly L. Davidson

PLoS One. 2012; 7(6): e38562. Published online 2012 Jun 11. doi: 10.1371/journal.pone.0038562

PMCID:: PMC3372529

Article PDF–2.6M

Select item 45775715.

Numb Regulates the Polarized Delivery of Cyclic Nucleotide-Gated Ion Channels in Rod Photoreceptor Cilia

Vasanth Ramamurthy, Christine Jolicoeur, Demetra Koutroumbas, Johanna Mühlhans, Yun-Zheng Le, William W. Hauswirth, Andreas Giessl, Michel Cayouette

J Neurosci. 2014 Oct 15; 34(42): 13976–13987. doi: 10.1523/JNEUROSCI.1938-14.2014

Correction in:: J Neurosci. 2015 Apr 15; 35(15): 6254.

PMCID:: PMC4577571

Article PDF–5.3M

Select item 31037486.

Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis

Pengcheng Zhou, Jose Alfaro, Eun Hyuk Chang, Xuesong Zhao, Marimelia Porcionatto, Rosalind A. Segal

Dev Cell. Author manuscript; available in PMC 2012 May 17.

Published in final edited form as: Dev Cell. 2011 May 17; 20(5): 610–622. doi: 10.1016/j.devcel.2011.04.006

PMCID:: PMC3103748

Article PDF–2.4M

Select item 46397987.

Numb is required to prevent p53-dependent senescence following skeletal muscle injury

Isabelle Le Roux, Julie Konge, Laurent Le Cam, Patricia Flamant, Shahragim Tajbakhsh

Nat Commun. 2015; 6: 8528. Published online 2015 Oct 27. doi: 10.1038/ncomms9528

PMCID:: PMC4639798

Article PDF–3.8M

Select item 38319588.

Numb-deficient satellite cells have regeneration and proliferation defects

Rajani M. George, Stefano Biressi, Brian J. Beres, Erik Rogers, Amanda K. Mulia, Ronald E. Allen, Alan Rawls, Thomas A. Rando, Jeanne Wilson-Rawls

Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46): 18549–18554. Published online 2013 Oct 29. doi: 10.1073/pnas.1311628110

PMCID:: PMC3831958

Article PDF–1.2M

Select item 95814859.

Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models

Marine Lacomme, Sarah C. Hales, Thomas W. Brown, Katarina Stevanovic, Christine Jolicoeur, Jenny Cai, Therence Bois, Melissa Desrosiers, Deniz Dalkara, Michel Cayouette

Sci Adv. 2022 Oct; 8(42): eabm4295. Published online 2022 Oct 19. doi: 10.1126/sciadv.abm4295

PMCID:: PMC9581485

Article PDF–12M

Select item 592471710.

β1-integrin Is a Cell-Autonomous Factor Mediating the Numb Pathway for Cardiac Progenitor Maintenance

Brian Gibbs, Lincoln Shenje, Peter Andersen, Matthew Miyamoto, Chulan Kwon

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Jun 2.

Published in final edited form as: Biochem Biophys Res Commun. 2018 Jun 2; 500(2): 256–260. Published online 2018 Apr 13. doi: 10.1016/j.bbrc.2018.04.054

PMCID:: PMC5924717

Article PDF–848K

Select item 187676511.

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche.

Chay T. Kuo, Zaman Mirzadeh, Mario Soriano-Navarro, Mladen Rašin, Denan Wang, Jie Shen, Nenad Šestan, Jose Garcia-Verdugo, Arturo Alvarez-Buylla, Lily Y. Jan, Yuh-Nung Jan

Cell. Author manuscript; available in PMC 2007 Dec 15.

Published in final edited form as: Cell. 2006 Dec 15; 127(6): 1253–1264. doi: 10.1016/j.cell.2006.10.041

PMCID:: PMC1876765

Article PDF–1023K

Select item 429167712.

Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling

Gaurav Swarnkar, Kannan Karuppaiah, Gabriel Mbalaviele, Tim (Hung-Po) Chen, Yousef Abu-Amer

Proc Natl Acad Sci U S A. 2015 Jan 6; 112(1): 154–159. Published online 2014 Dec 22. doi: 10.1073/pnas.1415213112

PMCID:: PMC4291677

Article PDF–1.3M

Select item 400720613.

Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors

Lincoln T Shenje, Peter Andersen, Hideki Uosaki, Laviel Fernandez, Peter P Rainer, Gun-sik Cho, Dong-ik Lee, Weimin Zhong, Richard P Harvey, David A Kass, Chulan Kwon

eLife. 2014; 3: e02164. Published online 2014 Apr 24. doi: 10.7554/eLife.02164

PMCID:: PMC4007206

Article PDF–4.2M

Select item 672011114.

Exosomal microRNA transport from salivary mesenchyme regulates epithelial progenitor expansion during organogenesis.

Toru Hayashi, Isabelle M.A. Lombaert, Belinda R. Hauser, Vaishali N. Patel, Matthew P. Hoffman

Dev Cell. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Dev Cell. 2017 Jan 9; 40(1): 95–103. Published online 2016 Dec 29. doi: 10.1016/j.devcel.2016.12.001

PMCID:: PMC6720111

Article PDF–773K

Select item 545084915.

Numb regulates somatic cell lineage commitment during early gonadogenesis in mice

Yi-Tzu Lin, Lindsey Barske, Tony DeFalco, Blanche Capel

Development. 2017 May 1; 144(9): 1607–1618. doi: 10.1242/dev.149203

PMCID:: PMC5450849

Article

Select item 847113616.

The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis

Lianjie Miao, Yangyang Lu, Anika Nusrat, Hala Y. Abdelnasser, Sayantap Datta, Bin Zhou, Robert J. Schwartz, Mingfu Wu

Cells. 2021 Sep; 10(9): 2192. Published online 2021 Aug 25. doi: 10.3390/cells10092192

PMCID:: PMC8471136

Article PDF–8.0M

Select item 562674917.

NUMBL Interacts with TAK1, TRAF6 and NEMO to Negatively Regulate NF-κB Signaling During Osteoclastogenesis

Gaurav Swarnkar, Tim Hung-Po Chen, Manoj Arra, Amjad M. Nasir, Gabriel Mbalaviele, Yousef Abu-Amer

Sci Rep. 2017; 7: 12600. Published online 2017 Oct 3. doi: 10.1038/s41598-017-12707-7

PMCID:: PMC5626749

Article PDF–3.8M

Select item 54023218.

Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization

Eric J. Huang, Huashun Li, Amy A. Tang, Amanda K. Wiggins, Rachael L. Neve, Weimin Zhong, Lily Y. Jan, Yuh Nung Jan

Genes Dev. 2005 Jan 1; 19(1): 138–151. doi: 10.1101/gad.1246005

PMCID:: PMC540232

Article PDF–738K

Select item 668173619.

Cardiomyocyte orientation modulated by the Numb family proteins–N-cadherin axis is essential for ventricular wall morphogenesis

Lianjie Miao, Jingjing Li, Jian Li, Yangyang Lu, David Shieh, Joseph E. Mazurkiewicz, Margarida Barroso, John J. Schwarz, Hong-Bo Xin, Harold A. Singer, Peter A. Vincent, Weimin Zhong, Glenn L. Radice, Leo Q. Wan, Zhen-Chuan Fan, Guoying Huang, Mingfu Wu

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15560–15569. Published online 2019 Jul 12. doi: 10.1073/pnas.1904684116