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Items: 1 to 20 of 48

1.
A crucial exosome-related gene pair (AAMP and ABAT) is associated with inflammatory cells in intervertebral disc degeneration
Huiyong Ren, Yumin Li, Hao Liu, Jiaxin Fan, Jie Li, Haopeng Li, Hongyu Wei, Liesu Meng, Shuai Cao
Front Immunol. 2023; 14: 1160801. Published online 2023 Apr 14. doi: 10.3389/fimmu.2023.1160801
PMCID:
PMC10140513
ArticlePDF–6.6M
2.
AAMP promotes colorectal cancermetastasis by suppressing SMURF2-mediatedubiquitination and degradation of RhoA
Yuhui Wu, Bofang Liu, Weiqiang Lin, Rongjie Zhao, Weidong Han, Jiansheng Xie
Mol Ther Oncolytics. 2021 Dec 17; 23: 515–530. Published online 2021 Nov 11. doi: 10.1016/j.omto.2021.11.007
PMCID:
PMC8633529
ArticlePDF–5.4M
3.
The E3 Ubiquitin Ligase Thyroid Hormone Receptor-interacting Protein 12 Targets Pancreas Transcription Factor 1a for Proteasomal Degradation
Naïma Hanoun, Samuel Fritsch, Odile Gayet, Véronique Gigoux, Pierre Cordelier, Nelson Dusetti, Jérôme Torrisani, Marlène Dufresne
J Biol Chem. 2014 Dec 19; 289(51): 35593–35604. Published online 2014 Oct 29. doi: 10.1074/jbc.M114.620104
PMCID:
PMC4271242
ArticlePDF–1.6M
4.
Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer
Xuan Deng, Sihan Li, Fanyang Kong, Haoyu Ruan, Xiao Xu, Xinju Zhang, Zhiyuan Wu, Lin Zhang, Ying Xu, Hong Yuan, Haixia Peng, Da Yang, Ming Guan
Theranostics. 2020; 10(1): 265–280. Published online 2020 Jan 1. doi: 10.7150/thno.36045
PMCID:
PMC6929633
ArticlePDF–3.0M
5.
Genome-wide Association Studies of Pit-and-Fissure- and Smooth-surface Caries in Permanent Dentition
Z. Zeng, J.R. Shaffer, X. Wang, E. Feingold, D.E. Weeks, M. Lee, K.T. Cuenco, S.K. Wendell, R.J. Weyant, R. Crout, D.W. McNeil, M.L. Marazita
J Dent Res. 2013 May; 92(5): 432–437. doi: 10.1177/0022034513481976
PMCID:
PMC3627505
ArticlePDF–1.8M
6.
Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development
Yen-Fu Cheng, Mingjie Tong, Albert S. B. Edge
J Biol Chem. 2016 Sep 30; 291(40): 21096–21109. Published online 2016 Aug 19. doi: 10.1074/jbc.M116.722124
PMCID:
PMC5076519
ArticlePDF–3.4M
7.
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Carl A. Anderson, Gabrielle Boucher, Charlie W. Lees, Andre Franke, Mauro D’Amato, Kent D. Taylor, James C. Lee, Philippe Goyette, Marcin Imielinski, Anna Latiano, Caroline Lagacé, Regan Scott, Leila Amininejad, Suzannah Bumpstead, Leonard Baidoo, Robert N. Baldassano, Murray Barclay, Theodore M. Bayless, Stephan Brand, Carsten Büning, Jean-Frédéric Colombel, Lee A. Denson, Martine De Vos, Marla Dubinsky, Cathryn Edwards, David Ellinghaus, Rudolf S.N. Fehrmann, James A.B. Floyd, Tim Florin, Denis Franchimont, Lude Franke, Michel Georges, Jürgen Glas, Nicole L. Glazer, Stephen L. Guthery, Talin Haritunians, Nicholas K. Hayward, Jean-Pierre Hugot, Gilles Jobin, Debby Laukens, Ian Lawrance, Marc Lémann, Arie Levine, Cecile Libioulle, Edouard Louis, Dermot P. McGovern, Monica Milla, Grant W. Montgomery, Katherine I. Morley, Craig Mowat, Aylwin Ng, William Newman, Roel A Ophoff, Laura Papi, Orazio Palmieri, Laurent Peyrin-Biroulet, Julián Panés, Anne Phillips, Natalie J. Prescott, Deborah D. Proctor, Rebecca Roberts, Richard Russell, Paul Rutgeerts, Jeremy Sanderson, Miquel Sans, Philip Schumm, Frank Seibold, Yashoda Sharma, Lisa Simms, Mark Seielstad, A. Hillary Steinhart, Stephan R. Targan, Leonard H. van den Berg, Morten Vatn, Hein Verspaget, Thomas Walters, Cisca Wijmenga, David C. Wilson, Harm-Jan Westra, Ramnik J. Xavier, Zhen Z. Zhao, Cyriel Y. Ponsioen, Vibeke Andersen, Leif Torkvist, Maria Gazouli, Nicholas P. Anagnou, Tom H. Karlsen, Limas Kupcinskas, Jurgita Sventoraityte, John C. Mansfield, Subra Kugathasan, Mark S. Silverberg, Jonas Halfvarson, Jerome I. Rotter, Christopher G. Mathew, Anne M. Griffiths, Richard Gearry, Tariq Ahmad, Steven R. Brant, Mathias Chamaillard, Jack Satsangi, Judy H. Cho, Stefan Schreiber, Mark J. Daly, Jeffrey C. Barrett, Miles Parkes, Vito Annese, Hakon Hakonarson, Graham Radford-Smith, Richard H. Duerr, Séverine Vermeire, Rinse K. Weersma, John D. Rioux
Nat Genet. Author manuscript; available in PMC 2011 Sep 1.
Published in final edited form as: Nat Genet. 2011 Mar; 43(3): 246–252. Published online 2011 Feb 6. doi: 10.1038/ng.764
Correction in:
volume 43 on page 919
PMCID:
PMC3084597
ArticlePDF–404K
8.
Interactome mapping suggests new mechanistic details underlying Alzheimer's disease
Montserrat Soler-López, Andreas Zanzoni, Ricart Lluís, Ulrich Stelzl, Patrick Aloy
Genome Res. 2011 Mar; 21(3): 364–376. doi: 10.1101/gr.114280.110
PMCID:
PMC3044851
ArticlePDF–2.1M
9.
A conserved acetylation switch enables pharmacological control of tubby-like protein stability
Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard
J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839
PMCID:
PMC7948452
ArticlePDF–3.6M
10.
Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling
Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson
eLife. 2020; 9: e57306. Published online 2020 Jul 2. doi: 10.7554/eLife.57306
PMCID:
PMC7332293
ArticlePDF–2.2M
11.
Proteomic Analysis of the Epidermal Growth Factor Receptor (EGFR) Interactome and Post-translational Modifications Associated with Receptor Endocytosis in Response to EGF and Stress
Jiefei Tong, Paul Taylor, Michael F. Moran
Mol Cell Proteomics. 2014 Jul; 13(7): 1644–1658. Published online 2014 May 5. doi: 10.1074/mcp.M114.038596
PMCID:
PMC4083106
ArticlePDF–2.6M
12.
A role for mitochondrial translation in promotion of viability in K-Ras mutant cells
Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge
Cell Rep. Author manuscript; available in PMC 2017 Aug 11.
Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061
PMCID:
PMC5553568
ArticlePDF–1.8M
13.
Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease
Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu
Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1
PMCID:
PMC7301499
ArticlePDF–14M
14.
SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response
Syed Nabeel-Shah, Hyunmin Lee, Nujhat Ahmed, Giovanni L. Burke, Shaghayegh Farhangmehr, Kanwal Ashraf, Shuye Pu, Ulrich Braunschweig, Guoqing Zhong, Hong Wei, Hua Tang, Jianyi Yang, Edyta Marcon, Benjamin J. Blencowe, Zhaolei Zhang, Jack F. Greenblatt
iScience. 2022 Jan 21; 25(1): 103562. Published online 2021 Dec 4. doi: 10.1016/j.isci.2021.103562
PMCID:
PMC8642831
ArticlePDF–5.2M
15.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
ArticlePDF–1.3M
16.
A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing
Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl
Nat Commun. 2022; 13: 1132. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28754-2
PMCID:
PMC8894380
ArticlePDF–5.6M
17.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116
Correction in:
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.
PMCID:
PMC6600915
ArticlePDF–1.7M
18.
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
Xiahui Li, Shujing Li, Bowen Li, Yanan Li, Sattout Aman, Kangkai Xia, Yuxi Yang, Bashir Ahmad, Huijian Wu
NPJ Precis Oncol. 2021; 5: 20. Published online 2021 Mar 19. doi: 10.1038/s41698-021-00158-3
PMCID:
PMC7979705
ArticlePDF–6.8M
19.
Charting the Landscape of Tandem BRCT Domain-Mediated Protein Interactions
Nicholas T. Woods, Rafael D. Mesquita, Michael Sweet, Marcelo A. Carvalho, Xueli Li, Yun Liu, Huey Nguyen, C. Eric Thomas, Edwin S. Iversen, Jr., Sylvia Marsillac, Rachel Karchin, John Koomen, Alvaro N.A. Monteiro
Sci Signal. Author manuscript; available in PMC 2014 Jun 20.
Published in final edited form as: Sci Signal. 2012; 5(242): rs6. Published online 2012 Sep 18. doi: 10.1126/scisignal.2002255
PMCID:
PMC4064718
ArticlePDF–2.1M
20.
Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion
Hyeon Gyu Seo, Han Byeol Kim, Ji Young Yoon, Tae Hyun Kweon, Yun Soo Park, Jingu Kang, Jinwoo Jung, SeongJin Son, Eugene C. Yi, Tae Ho Lee, Won Ho Yang, Jin Won Cho
Cell Death Dis. 2020 Sep; 11(9): 815. Published online 2020 Sep 29. doi: 10.1038/s41419-020-02999-5
PMCID:
PMC7525441
ArticlePDF–3.7M

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