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Select item 30960371.

Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts

Anuja Guria, Doan Duy Hai Tran, Sheetal Ramachandran, Alexandra Koch, Omar El Bounkari, Priyanka Dutta, Hansjörg Hauser, Teruko Tamura

RNA. 2011 Jun; 17(6): 1048–1056. doi: 10.1261/rna.2607011

PMCID:: PMC3096037

Article PDF–480K

Select item 42225862.

THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier

Shashank Saran, Doan DH Tran, Sabine Klebba-Färber, Patricia Moran-Losada, Lutz Wiehlmann, Alexandra Koch, Himpriya Chopra, Oliver Pabst, Andrea Hoffmann, Robert Klopfleisch, Teruko Tamura

BMC Cell Biol. 2013; 14: 51. Published online 2013 Nov 22. doi: 10.1186/1471-2121-14-51

PMCID:: PMC4222586

Article PDF–1.7M

Select item 39209563.

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation

D DH Tran, S Saran, O Dittrich-Breiholz, A JK Williamson, S Klebba-Färber, A Koch, M Kracht, A D Whetton, T Tamura

Cell Death Dis. 2013 Oct; 4(10): e879. Published online 2013 Oct 24. doi: 10.1038/cddis.2013.409

PMCID:: PMC3920956

Article PDF–3.1M

Select item 39701434.

Murine Leukemia Virus Uses TREX Components for Efficient Nuclear Export of Unspliced Viral Transcripts

Toshie Sakuma, Jason M. Tonne, Yasuhiro Ikeda

Viruses. 2014 Mar; 6(3): 1135–1148. Published online 2014 Mar 10. doi: 10.3390/v6031135

PMCID:: PMC3970143

Article PDF–460K

Select item 28062475.

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo

Annalisa Mancini, Susanne C Niemann-Seyde, Rüdiger Pankow, Omar El Bounkari, Sabine Klebba-Färber, Alexandra Koch, Ewa Jaworska, Elaine Spooncer, Achim D Gruber, Anthony D Whetton, Teruko Tamura

BMC Biol. 2010; 8: 1. Published online 2010 Jan 5. doi: 10.1186/1741-7007-8-1

PMCID:: PMC2806247

Article PDF–3.2M

Select item 65425606.

The THO complex coordinates transcripts for synapse development and dopamine neuron survival

Celine I. Maeder, Jae-Ick Kim, Xing Liang, Konstantin Kaganovsky, Ao Shen, Qin Li, Zhaoyu Li, Sui Wang, X.Z. Shawn Xu, Jin Billy Li, Yang Kevin Xiang, Jun B. Ding, Kang Shen

Cell. Author manuscript; available in PMC 2019 May 30.

Published in final edited form as: Cell. 2018 Sep 6; 174(6): 1436–1449.e20. Published online 2018 Aug 23. doi: 10.1016/j.cell.2018.07.046

PMCID:: PMC6542560

Article PDF–1.4M

Select item 108532167.

Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment

Rudrarup Bhattacharjee, Lachlan A. Jolly, Mark A. Corbett, Ing Chee Wee, Sushma R. Rao, Alison E. Gardner, Tarin Ritchie, Eline J. H. van Hugte, Ummi Ciptasari, Sandra Piltz, Jacqueline E. Noll, Nazzmer Nazri, Clare L. van Eyk, Melissa White, Dani Fornarino, Cathryn Poulton, Gareth Baynam, Lyndsey E. Collins-Praino, Marten F. Snel, Nael Nadif Kasri, Kim M. Hemsley, Paul Q. Thomas, Raman Kumar, Jozef Gecz

Nat Commun. 2024; 15: 1210. Published online 2024 Feb 8. doi: 10.1038/s41467-024-45121-5

PMCID:: PMC10853216

Article PDF–11M

Select item 39627958.

The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-renewal and Somatic Cell Reprogramming

Li Wang, Yi-liang Miao, Xiaofeng Zheng, Brad Lackford, Bingying Zhou, Leng Han, Chengguo Yao, James Ward, Adam Burkholder, Inna Lipchina, David C. Fargo, Konrad Hochedlinger, Yongsheng Shi, Carmen J. Williams, Guang Hu

Cell Stem Cell. Author manuscript; available in PMC 2014 Dec 5.

Published in final edited form as: Cell Stem Cell. 2013 Dec 5; 13(6): 676–690. doi: 10.1016/j.stem.2013.10.008

PMCID:: PMC3962795

Article PDF–3.2M

Select item 34043899.

Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain

Donny D. Licatalosi, Masato Yano, John J. Fak, Aldo Mele, Sarah E. Grabinski, Chaolin Zhang, Robert B. Darnell

Genes Dev. 2012 Jul 15; 26(14): 1626–1642. doi: 10.1101/gad.191338.112

PMCID:: PMC3404389

Article PDF–3.4M

Select item 330776210.

Functional Consequences of Necdin Nucleocytoplasmic Localization

Anat Lavi-Itzkovitz, Marianna Tcherpakov, Zehava Levy, Shalev Itzkovitz, Francoise Muscatelli, Mike Fainzilber

PLoS One. 2012; 7(3): e33786. Published online 2012 Mar 19. doi: 10.1371/journal.pone.0033786

PMCID:: PMC3307762

Article PDF–780K

Select item 451183311.

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia

Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga

Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859

PMCID:: PMC4511833

Article PDF–2.2M

Select item 309339512.

RAD21 Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity

Anja Nitzsche, Maciej Paszkowski-Rogacz, Filomena Matarese, Eva M. Janssen-Megens, Nina C. Hubner, Herbert Schulz, Ingrid de Vries, Li Ding, Norbert Huebner, Matthias Mann, Hendrik G. Stunnenberg, Frank Buchholz

PLoS One. 2011; 6(5): e19470. Published online 2011 May 12. doi: 10.1371/journal.pone.0019470

PMCID:: PMC3093395

Article PDF–1.0M

Select item 452520313.

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells

Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger

Nat Commun. 2015; 6: 7776. Published online 2015 Jul 24. doi: 10.1038/ncomms8776

PMCID:: PMC4525203

Article PDF–1.9M

Select item 1683314.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Article PDF–847K

Select item 255627015.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Article PDF–493K

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Article PDF–1.1M

Select item 28355417.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Article PDF–481K

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Article PDF–3.8M

Select item 31099219.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Article PDF–3.4M

Select item 31098020.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Article PDF–1.4M

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