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Select item 84445771.

IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis

Hong Ki Min, Sehee Kim, Ji-Yeon Lee, Kyoung-Woon Kim, Sang-Heon Lee, Hae-Rim Kim

J Transl Med. 2021; 19: 392. Published online 2021 Sep 16. doi: 10.1186/s12967-021-03071-2

PMCID:: PMC8444577

Article PDF–2.3M

Select item 50304842.

IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation

Mohd Nizam Mansoori, Priyanka Shukla, Manisha Kakaji, Abdul M Tyagi, Kamini Srivastava, Manoj Shukla, Manisha Dixit, Jyoti Kureel, Sushil Gupta, Divya Singh

Sci Rep. 2016; 6: 33680. Published online 2016 Sep 21. doi: 10.1038/srep33680

PMCID:: PMC5030484

Article PDF–2.2M

Select item 28001853.

Failure of Interferon γ to Induce the Anti-Inflammatory Interleukin 18 Binding Protein in Familial Hemophagocytosis

Claudia A. Nold-Petry, Thomas Lehrnbecher, Andrea Jarisch, Dirk Schwabe, Josef M. Pfeilschifter, Heiko Muhl, Marcel F. Nold

PLoS One. 2010; 5(1): e8663. Published online 2010 Jan 13. doi: 10.1371/journal.pone.0008663

PMCID:: PMC2800185

Article PDF–297K

Select item 17666794.

Novel targets for interleukin 18 binding protein

C Dinarello

Ann Rheum Dis. 2001 Nov; 60(Suppl 3): iii18–iii24. doi: 10.1136/ard.60.90003.iii18

PMCID:: PMC1766679

Summary PDF–144K

Select item 98899895.

Interleukin-18 and IL-18BP in inflammatory dermatological diseases

Xiaoyun Wang, Lian Wang, Xiang Wen, Lu Zhang, Xian Jiang, Gu He

Front Immunol. 2023; 14: 955369. Published online 2023 Jan 18. doi: 10.3389/fimmu.2023.955369

PMCID:: PMC9889989

Article PDF–2.3M

Select item 91119896.

Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity

Sam Detry, Julie Andries, Yehudi Bloch, Cem Gabay, Danielle M. Clancy, Savvas N. Savvides

J Biol Chem. 2022 May; 298(5): 101908. Published online 2022 Apr 6. doi: 10.1016/j.jbc.2022.101908

PMCID:: PMC9111989

Article PDF–4.7M

Select item 85248707.

IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria

Kari Otterdal, Aase Berg, Annika E. Michelsen, Arne Yndestad, Sam Patel, Ida Gregersen, Bente Halvorsen, Thor Ueland, Nina Langeland, Pål Aukrust

BMC Infect Dis. 2021; 21: 1073. Published online 2021 Oct 18. doi: 10.1186/s12879-021-06751-y

PMCID:: PMC8524870

Article PDF–2.8M

Select item 65299788.

Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

Malte Bachmann, Jens Paulukat, Josef Pfeilschifter, Heiko Mühl

J Cell Mol Med. 2009 Aug; 13(8b): 1987–1994. Published online 2008 Nov 28. doi: 10.1111/j.1582-4934.2008.00604.x

PMCID:: PMC6529978

Article PDF–698K

Select item 34589159.

Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia

Ilaria Palladino, Francesca Salani, Antonio Ciaramella, Ivo Alex Rubino, Carlo Caltagirone, Sabrina Fagioli, Gianfranco Spalletta, Paola Bossù

J Neuroinflammation. 2012; 9: 206. Published online 2012 Aug 22. doi: 10.1186/1742-2094-9-206

PMCID:: PMC3458915

Article PDF–332K

Select item 301091310.

Interfering with interferon-γ signalling in intestinal epithelial cells: selective inhibition of apoptosis-maintained secretion of anti-inflammatory interleukin-18 binding protein

D Schuhmann, P Godoy, C Weiß, A Gerloff, M V Singer, S Dooley, U Böcker

Clin Exp Immunol. 2011 Jan; 163(1): 65–76. doi: 10.1111/j.1365-2249.2010.04250.x

PMCID:: PMC3010913

Article PDF–1.3M

Select item 1556411.

Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

Soo-Hyun Kim, Miriam Eisenstein, Leonid Reznikov, Giamila Fantuzzi, Daniela Novick, Menachem Rubinstein, Charles A. Dinarello

Proc Natl Acad Sci U S A. 2000 Feb 1; 97(3): 1190–1195. doi: 10.1073/pnas.97.3.1190

PMCID:: PMC15564

Article PDF–392K

Select item 405210612.

Expression of IL-18, IL-18 Binding Protein, and IL-18 Receptor by Normal and Cancerous Human Ovarian Tissues: Possible Implication of IL-18 in the Pathogenesis of Ovarian Carcinoma

Liat Medina, Alex Rabinovich, Benjamin Piura, Victor Dyomin, Ruthy Shaco Levy, Mahmoud Huleihel

Mediators Inflamm. 2014; 2014: 914954. Published online 2014 May 15. doi: 10.1155/2014/914954

PMCID:: PMC4052106

Article PDF–4.0M

Select item 399375013.

Human Papillomavirus E7 Oncoprotein Increases Production of the Anti-Inflammatory Interleukin-18 Binding Protein in Keratinocytes

Kathryn H. Richards, Rosella Doble, Christopher W. Wasson, Mohammed Haider, G. Eric Blair, Miriam Wittmann, Andrew Macdonald

J Virol. 2014 Apr; 88(8): 4173–4179. doi: 10.1128/JVI.02546-13

PMCID:: PMC3993750

Article PDF–575K

Select item 12975514.

A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity

Philip Bufler, Tania Azam, Fabia Gamboni-Robertson, Leonid L. Reznikov, Sanjay Kumar, Charles A. Dinarello, Soo-Hyun Kim

Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21): 13723–13728. doi: 10.1073/pnas.212519099

PMCID:: PMC129755

Article PDF–322K

Select item 13925115.

The promoter of IL-18 binding protein: Activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein β

Vladimir Hurgin, Daniela Novick, Menachem Rubinstein

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16957–16962. Published online 2002 Dec 13. doi: 10.1073/pnas.262663399

PMCID:: PMC139251

Article PDF–308K

Select item 574268716.

Role of IL‐18 in atopic asthma is determined by balance of IL‐18/IL‐18BP/IL‐18R

Huiyun Zhang, Junling Wang, Ling Wang, Hua Xie, Liping Chen, Shaoheng He

J Cell Mol Med. 2018 Jan; 22(1): 354–373. Published online 2017 Sep 18. doi: 10.1111/jcmm.13323

PMCID:: PMC5742687

Article PDF–2.6M

Select item 285372117.

Large-Scale candidate gene analysis of spontaneous hepatitis C virus clearance

Timothy L Mosbruger, Priya Duggal, James J. Goedert, Gregory D Kirk, W. Keith Hoots, Leslie H Tobler, Michael Busch, Marion G. Peters, Hugo R Rosen, David L Thomas, Chloe L Thio

J Infect Dis. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: J Infect Dis. 2010 May 1; 201(9): 1371–1380. doi: 10.1086/651606

PMCID:: PMC2853721

Article PDF–159K

Select item 360488918.

Identification of Fetal and Maternal Single Nucleotide Polymorphisms in Candidate Genes That Predispose to Spontaneous Preterm Labor with Intact Membranes

Roberto Romero, Digna R. Velez, Juan Pedro Kusanovic, Sonia S. Hassan, Shali Mazaki-Tovi, Edi Vaisbuch, Chong Jai Kim, Tinnakorn Chaiworapongsa, Brad Pearce, Lara A. Friel, Jacquelaine Bartlett, Madan Kumar Anant, Benjamin A. Salisbury, Gerald F. Vovis, Min Seob Lee, Ricardo Gomez, Ernesto Behnke, Enrique Oyarzun, Gerard Tromp, Scott M. Williams, Ramkumar Menon

Am J Obstet Gynecol. Author manuscript; available in PMC 2013 Mar 21.

Published in final edited form as: Am J Obstet Gynecol. 2010 May; 202(5): 431.e1–431.34. doi: 10.1016/j.ajog.2010.03.026

PMCID:: PMC3604889

Article PDF–4.4M

Select item 298966219.

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)

Roberto ROMERO, Lara A. FRIEL, Digna R. VELEZ EDWARDS, Juan Pedro KUSANOVIC, Sonia S. HASSAN, Shali MAZAKI-TOVI, Edi VAISBUCH, Chong Jai KIM, Offer EREZ, Tinnakorn CHAIWORAPONGSA, Brad D. PEARCE, Jacquelaine BARTLETT, Benjamin A. SALISBURY, Madan Kumar ANANT, Gerald F. VOVIS, Min Seob LEE, Ricardo GOMEZ, Ernesto BEHNKE, Enrique OYARZUN, Gerard TROMP, Scott M. WILLIAMS, Ramkumar MENON

Am J Obstet Gynecol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Am J Obstet Gynecol. 2010 Oct; 203(4): 361.e1–361.e30. Published online 2010 Jul 31. doi: 10.1016/j.ajog.2010.05.026

PMCID:: PMC2989662

Article PDF–640K

Select item 228655120.

Signal peptide prediction based on analysis of experimentally verified cleavage sites

Zemin Zhang, William J. Henzel

Protein Sci. 2004 Oct; 13(10): 2819–2824. doi: 10.1110/ps.04682504

PMCID:: PMC2286551

Article PDF–125K

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