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Select item 88100721.

Hypomethylation-driven AKT Serine/Threonine Kinase 3 promotes testicular germ cell tumors proliferation and negatively correlates to immune infiltration

Yang Luo, Qianyin Zhou, Fang Zhu, Liqing Fan, Hao Bo, Xingming Wang

Bioengineered. 2021; 12(2): 11288–11302. Published online 2021 Dec 9. doi: 10.1080/21655979.2021.2002621

PMCID:: PMC8810072

Article PDF–4.2M

Select item 87330552.

Cutaneous vascular anomalies associated with mosaic variant in AKT3; Genetic analysis continues to refine diagnosis, nomenclature, and classification of vascular anomalies

Olivia M.T. Davies, Maria C. Garzon, Ilona J. Frieden, Catherine E. Cottrell, Karen W. Gripp, Russell P. Saneto, Tor Shwayder, Ghayda M. Mirzaa, Beth A. Drolet

J Am Acad Dermatol. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: J Am Acad Dermatol. 2022 Jul; 87(1): 162–164. Published online 2021 Jul 6. doi: 10.1016/j.jaad.2021.06.877

PMCID:: PMC8733055

Article PDF–182K

Select item 81777803.

AKT3 is a key regulator of head and neck squamous cell carcinoma

Hideyuki Takahashi, Susumu Rokudai, Reika Kawabata‐Iwakawa, Koichi Sakakura, Tetsunari Oyama, Masahiko Nishiyama, Kazuaki Chikamatsu

Cancer Sci. 2021 Jun; 112(6): 2325–2334. Published online 2021 May 1. doi: 10.1111/cas.14911

PMCID:: PMC8177780

Article PDF–1.0M

Select item 79062064.

Hsa_circ_0000199 facilitates chemo-tolerance of triple-negative breast cancer by interfering with miR-206/613-led PI3K/Akt/mTOR signaling

Hongchang Li, Wen Xu, Zhihua Xia, Weiyan Liu, Gaofeng Pan, Junbin Ding, Jindong Li, Jianfa Wang, Xiaofeng Xie, Daowen Jiang

Aging (Albany NY) 2021 Feb 15; 13(3): 4522–4551. Published online 2021 Jan 20. doi: 10.18632/aging.202415

PMCID:: PMC7906206

Article PDF–3.2M

Select item 77269145.

circAKT3 positively regulates osteogenic differentiation of human dental pulp stromal cells via miR-206/CX43 axis

Bo Zhang, Sibei Huo, Xiao Cen, Xuefeng Pan, Xinqi Huang, Zhihe Zhao

Stem Cell Res Ther. 2020; 11: 531. Published online 2020 Dec 9. doi: 10.1186/s13287-020-02058-y

PMCID:: PMC7726914

Article PDF–4.8M

Select item 75018786.

An Akt3 splice variant lacking the serine 472 phosphorylation site promotes apoptosis and suppresses mammary tumorigenesis

Kimita Suyama, Jiahong Yao, Huizhi Liang, Outhiriaradjou Benard, Olivier Loudig, Dulguun Amgalan, Wendy M. McKimpson, Greg R. Phillips, Jeffrey Segall, Yihong Wang, Susan Fineberg, Larry Norton, Richard N. Kitsis, Rachel B. Hazan

Cancer Res. Author manuscript; available in PMC 2020 Sep 19.

Published in final edited form as: Cancer Res. 2018 Jan 1; 78(1): 103–114. Published online 2017 Oct 16. doi: 10.1158/0008-5472.CAN-15-1462

PMCID:: PMC7501878

Article PDF–1.1M

Select item 68241047.

Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals

Dingwei Xue, Huan Wang, Yuanlei Chen, Danyang Shen, Jieyang Lu, Mingchao Wang, Abudureheman Zebibula, Liwei Xu, Haiyang Wu, Gonghui Li, Liqun Xia

Mol Cancer. 2019; 18: 151. Published online 2019 Nov 1. doi: 10.1186/s12943-019-1072-5

PMCID:: PMC6824104

Article PDF–3.0M

Select item 60848578.

Diagnostic value of partial exome sequencing in developmental disorders

Laura Gieldon, Luisa Mackenroth, Anne-Karin Kahlert, Johannes R. Lemke, Joseph Porrmann, Jens Schallner, Maja von der Hagen, Susanne Markus, Sabine Weidensee, Barbara Novotna, Charlotte Soerensen, Barbara Klink, Johannes Wagner, Andreas Tzschach, Arne Jahn, Franziska Kuhlee, Karl Hackmann, Evelin Schrock, Nataliya Di Donato, Andreas Rump

PLoS One. 2018; 13(8): e0201041. Published online 2018 Aug 9. doi: 10.1371/journal.pone.0201041

Correction in:: PLoS One. 2020; 15(9): e0239959.

PMCID:: PMC6084857

Article PDF–1.1M

Select item 60804239.

Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly

Diana Alcantara, Andrew E Timms, Karen Gripp, Laura Baker, Kaylee Park, Sarah Collins, Chi Cheng, Fiona Stewart, Sarju G Mehta, Anand Saggar, László Sztriha, Melinda Zombor, Oana Caluseriu, Ronit Mesterman, Margot I Van Allen, Adeline Jacquinet, Sofia Ygberg, Jonathan A Bernstein, Aaron M Wenger, Harendra Guturu, Gill Bejerano, Natalia Gomez-Ospina, Anna Lehman, Enrico Alfei, Chiara Pantaleoni, Valerio Conti, Renzo Guerrini, Ute Moog, John M Graham Jr., Robert Hevner, William B Dobyns, Mark O’Driscoll, Ghayda M Mirzaa

Brain. 2017 Oct; 140(10): 2610–2622. Published online 2017 Sep 7. doi: 10.1093/brain/awx203

PMCID:: PMC6080423

Article PDF–907K

Select item 604229710.

A novel functional splice variant of AKT3 defined by analysis of alternative splice expression in HPV-positive oropharyngeal cancers

Theresa Guo, Akihiro Sakai, Bahman Afsari, Michael Considine, Ludmila Danilova, Alexander V. Favorov, Srinivasan Yegnasubramanian, Dylan Z. Kelley, Emily Flam, Patrick K. Ha, Zubair Khan, Sarah J. Wheelan, J. Silvio Gutkind, Elana J. Fertig, Daria A. Gaykalova, Joseph Califano

Cancer Res. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Cancer Res. 2017 Oct 1; 77(19): 5248–5258. Published online 2017 Jul 21. doi: 10.1158/0008-5472.CAN-16-3106

PMCID:: PMC6042297

Article PDF–1.8M

Select item 497565011.

UPREGULATION OF AKT3 CONFERS RESISTANCE TO AKT INHIBITOR MK2206 IN BREAST CANCER

Casey Stottrup, Tiffany Tsang, Y. Rebecca Chin

Mol Cancer Ther. Author manuscript; available in PMC 2017 Aug 1.

Published in final edited form as: Mol Cancer Ther. 2016 Aug; 15(8): 1964–1974. Published online 2016 Jun 13. doi: 10.1158/1535-7163.MCT-15-0748

PMCID:: PMC4975650

Article PDF–1.1M

Select item 488835612.

Akt3 knockdown induces mitochondrial dysfunction in human cancer cells

Minjee Kim, Young Yeon Kim, Hye Jin Jee, Sun Sik Bae, Na Young Jeong, Jee-Hyun Um, Jeanho Yun

Acta Biochim Biophys Sin (Shanghai) 2016 May; 48(5): 447–453. Published online 2016 Mar 13. doi: 10.1093/abbs/gmw014

PMCID:: PMC4888356

Article PDF–427K

Select item 437192213.

Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression

Kristen M. Turner, Youting Sun, Ping Ji, Kirsi J. Granberg, Brady Bernard, Limei Hu, David E. Cogdell, Xinhui Zhou, Olli Yli-Harja, Matti Nykter, Ilya Shmulevich, W. K. Alfred Yung, Gregory N. Fuller, Wei Zhang

Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11): 3421–3426. Published online 2015 Mar 3. doi: 10.1073/pnas.1414573112

PMCID:: PMC4371922

Article PDF–1.6M

Select item 394650214.

TARGETING AKT3 SIGNALING IN TRIPLE NEGATIVE BREAST CANCER

Y. Rebecca Chin, Taku Yoshida, Andriy Marusyk, Andrew H. Beck, Kornelia Polyak, Alex Toker

Cancer Res. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Cancer Res. 2014 Feb 1; 74(3): 964–973. Published online 2013 Dec 12. doi: 10.1158/0008-5472.CAN-13-2175

PMCID:: PMC3946502

Article PDF–2.0M

Select item 346055115.

Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations

Annapurna Poduri, Gilad D. Evrony, Xuyu Cai, Princess Christina Elhosary, Rameen Beroukhim, Maria K. Lehtinen, L. Benjamin Hills, Erin L. Heinzen, Anthony Hill, R. Sean Hill, Brenda J. Barry, Blaise F.D. Bourgeois, James J. Riviello, A. James Barkovich, Peter M. Black, Keith L. Ligon, Christopher A. Walsh

Neuron. Author manuscript; available in PMC 2012 Oct 12.

Published in final edited form as: Neuron. 2012 Apr 12; 74(1): 41–48. doi: 10.1016/j.neuron.2012.03.010

PMCID:: PMC3460551

Article PDF–2.3M

Select item 257052516.

A novel AKT3 mutation in melanoma tumours and cell lines

M A Davies, K Stemke-Hale, C Tellez, T L Calderone, W Deng, V G Prieto, A J F Lazar, J E Gershenwald, G B Mills

Br J Cancer. 2008 Oct 21; 99(8): 1265–1268. Published online 2008 Sep 23. doi: 10.1038/sj.bjc.6604637

PMCID:: PMC2570525

Article PDF–129K

Select item 1005130117.

Autoantibodies against PIP4K2B and AKT3 Are Associated with Skin and Lung Fibrosis in Patients with Systemic Sclerosis

Marija Geroldinger-Simić, Shaghayegh Bayati, Emmie Pohjanen, Norbert Sepp, Peter Nilsson, Elisa Pin

Int J Mol Sci. 2023 Mar; 24(6): 5629. Published online 2023 Mar 15. doi: 10.3390/ijms24065629

PMCID:: PMC10051301

Article PDF–1.7M

Select item 863620218.

Circ_0016760 accelerates non‐small‐cell lung cancer progression through miR‐646/AKT3 signaling in vivo and in vitro

Shan Chen, Long Zhou, Ruizhi Ran, Jinqi Huang, Yong Zheng, Maohui Xing, Yanli Cai

Thorac Cancer. 2021 Dec; 12(23): 3223–3235. Published online 2021 Oct 17. doi: 10.1111/1759-7714.14191

PMCID:: PMC8636202

Article PDF–3.9M

Select item 837557119.

miR-145 suppresses thyroid cancer growth and metastasis and targets AKT3

Myriem Boufraqech, Lisa Zhang, Meenu Jain, Dhaval Patel, Ryan Ellis, Yin Xiong, Mei He, Naris Nilubol, Maria J Merino, Electron Kebebew

Endocr Relat Cancer. Author manuscript; available in PMC 2021 Aug 19.

Published in final edited form as: Endocr Relat Cancer. 2014 Aug; 21(4): 517–531. Published online 2014 Apr 29. doi: 10.1530/ERC-14-0077

PMCID:: PMC8375571

Article PDF–2.5M

Select item 837335520.

CircRNA WHSC1 promotes non‐small cell lung cancer progression via sponging microRNA‐296‐3p and up‐regulating expression of AKT serine/threonine kinase 3

Fengfeng Shi, Qin Yang, Dongdong Shen, Jianwei Chen

J Clin Lab Anal. 2021 Aug; 35(8): e23865. Published online 2021 Jul 27. doi: 10.1002/jcla.23865

PMCID:: PMC8373355

Article PDF–1.3M

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