Table 1
Top Hit Genes Identified in the shRNA Screen
The top 10 enriched and disenriched genes with Gene ID, Symbol, Gene Info and log transformed signed P Mann Whitney-value are shown.
| #GeneID | Symbol | GeneInfo | Signed log10 P | |
|---|---|---|---|---|
| Top 10 Enriched Genes | 387264 | KRTAP5-1 | Keratin Associated Protein 5-1 | 6.516 |
| 148170 | CDC42EP5 | CDC42 Effector Protein (Rho GTPase Binding) 5 | 4.515 | |
| 333932 | HIST2H3A | Histone Cluster 2, H3a | 4.51 | |
| 25827 | FBXL2 | F-box and Leucine-rich Repeat Protein 2 | 4.442 | |
| 25794 | FSCN2 | Fascin Homolog 2, Actin-bundling Protein, Retinal (Strongylocentrotus purpuratus) | 4.328 | |
| 147381 | CBLN2 | Cerebellin 2 Precursor | 4.015 | |
| 2176 | FANCC | Fanconi anemia, Complementation Group C | 3.795 | |
| 85235 | HIST1H2AH | Histone Cluster 1, H2ah | 3.751 | |
| 10006 | ABI1 | Abl-interactor 1 | 3.749 | |
| 4179 | CD46 | CD46 Molecule, Complement Regulatory Protein | 3.732 | |
| Top 10 Disenriched Genes | 148252 | DIRAS1 | DIRAS Family, GTP-binding RAS-like 1 | −13.326 |
| 114902 | C1QTNF5 | C1q and Tumor Necrosis Factor Related Protein 5 | −5.766 | |
| 1193 | CLIC2 | Chloride Intracellular Channel 2 | −5.666 | |
| 390667 | PTX4 | Pentraxin 4, Long | −5.466 | |
| 51005 | AMDHD2 | Amidohydrolase Domain Containing 2 | −5.301 | |
| 3630 | INS | Insulin | −4.797 | |
| 220004 | PPP1R32 | Chromosome 11 Open Reading Frame 66 | −4.755 | |
| 5473 | PPBP | Pro-platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) | −4.69 | |
| 284353 | NKPD1 | NTPase, KAP Family P-loop Domain Containing 1 | −4.686 | |
| 50632 | CALY | Calcyon Neuron-specific Vesicular Protein | −4.554 |
See also Tables S1, S2 and S3