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Table 2

Basic Cytokine Patterns

PatternCytokinesPattern Effect
TH1IFN-γ, IL-12, TNF-αStimulates immune response to cancer
TH2IL-4, IL-5, IL-13Decreases TH1
TH3/TregTGF-βModulates TH1
ProinflammatoryIL-1, IL-6, IL-8, TNF-αCauses inflammation