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Proc Natl Acad Sci U S A. 1978 Feb; 75(2): 905–908.
doi: 10.1073/pnas.75.2.905
PMCID: PMC411366
PMID: 16592501

Lucibufagins: Defensive steroids from the fireflies Photinus ignitus and P. marginellus (Coleoptera: Lampyridae)*

Thomas Eisner,† David F. Wiemer,‡ LeRoy W. Haynes,‡ and Jerrold Meinwald‡
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Abstract

Feeding tests with thrushes (Hylocichla spp.) led to the isolation of three novel steroid pyrones from fireflies (Photinus ignitus and P. marginellus) responsible, in part at least, for the unpalatability of these insects to the birds. The term lucibufagin is coined for these steroidal pyrones. The closest known relatives of lucibufagins are the familiar cardiotonic bufadienolides, found in certain toads and plants.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  • Eisner T, Hicks K, Eisner M, Robson DS. "Wolf-in-Sheep's-Clothing" Strategy of a Predaceous Insect Larva. Science. 1978 Feb 17;199(4330):790–794. [PubMed] [Google Scholar]
  • Carrel JE, Eisner T. Cantharidin: potent feeding deterrent to insects. Science. 1974 Feb 22;183(4126):755–757. [PubMed] [Google Scholar]
  • Meinwald J, Meinwald YC, Chalmers AM, Eisner T. Dihydromatricaria acid: acetylenic acid secreted by soldier beetle. Science. 1968 May 24;160(3830):890–892. [PubMed] [Google Scholar]
  • Gsell L, Tamm C. Magnetische Protonenresonanz-Spektroskopie der Bufadienolide (steroidartigen Krötengifte) Helv Chim Acta. 1969;52(2):551–568. [PubMed] [Google Scholar]
  • Reichstein T, von Euw J, Parsons JA, Rothschild M. Heart poisons in the monarch butterfly. Some aposematic butterflies obtain protection from cardenolides present in their food plants. Science. 1968 Aug 30;161(3844):861–866. [PubMed] [Google Scholar]
  • Rothschild M, von Euw J, Reichstein T. Cardiac glycosides in the oleander aphid, Aphis nerii. J Insect Physiol. 1970 Jun;16(6):1141–1145. [PubMed] [Google Scholar]
  • von Euw J, Fishelson L, Parsons JA, Reichstein T, Rothschild M. Cardenolides (heart poisons) in a grasshopper feeding on milkweeds. Nature. 1967 Apr 1;214(5083):35–39. [PubMed] [Google Scholar]
  • Pasteels JM, Daloze D. Cardiac glycosides in the defensive secretion of chrysomelid beetles: evidence for their production by the insects. Science. 1977 Jul 1;197(4298):70–72. [PubMed] [Google Scholar]
  • Schildknecht H, Birringer H. Uber Arthropoden-Abwehrstoffe. XLIV. Die Steroide des Schlammschwimmers Ilybius fenestratus, 3. Z Naturforsch B. 1969 Dec;24(12):1529–1534. [PubMed] [Google Scholar]
  • Brower LP, Glazier SC. Localization of heart poisons in the monarch butterfly. Science. 1975 Apr 4;188(4183):19–25. [PubMed] [Google Scholar]
  • Porto AM, Gros EG. Biosynthesis of the bufadienolide marinobufagin in toads Bufo paracnemis from cholesterol-20-14C. Experientia. 1971 May 15;27(5):506–506. [PubMed] [Google Scholar]
  • Brower LP, van Brower J, Corvino JM. Plant poisons in a terrestrial food chain. Proc Natl Acad Sci U S A. 1967 Apr;57(4):893–898. [PMC free article] [PubMed] [Google Scholar]
  • Brower LP, Ryerson WN, Coppinger LL, Glazier SC. Ecological chemistry and the palatability spectrum. Science. 1968 Sep 27;161(3848):1349–1350. [PubMed] [Google Scholar]
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