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Clin Diagn Lab Immunol. 1994 Mar; 1(2): 244–246.
doi: 10.1128/cdli.1.2.244-246.1994
PMCID: PMC368237
PMID: 7496955

Augmentation of anti-influenza virus hemagglutinin antibody production by Peyer's patch cells with Bifidobacterium breve YIT4064.

H Yasui, N Nagaoka, and K Hayakawa
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Abstract

Bifidobacterium breve YIT4064 was tested an an adjuvant for oral influenza vaccine by the murine Peyer's patch cell culture method. The organism augmented production of anti-influenza virus hemagglutinin immunoglobulin A antibody by Peyer's patch cells in response to addition of hemagglutinin. These antibodies may be disseminated to the respiratory mucosal tissue and prevent influenza virus infection.

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Selected References

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