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FIG. 1.

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Glycolysis and the citric acid cycle showing glucose and glutamine utilization. The aspects of the cytoplasmic (Cyto) and mitochondrial (Mito) metabolism of glucose and glutamine discussed in the text are outlined. Dashed lines indicate that there are several intermediates formed (several reactions) between the ones shown. PEPCK, phosphoenolpyruvate carboxykinase; ME: malic enzyme; GDH, glutamate dehydrogenase; GLS, glutaminase; ACL, ATP citrate lyase; OAA, oxaloacetic acid; AcCoA, acetyl coenzyme A.

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