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Items: 1 to 20 of 169

1.
Dynamic modelling of an ACADS genotype in fatty acid oxidation – Application of cellular models for the analysis of common genetic variants
Kerstin Matejka, Ferdinand Stückler, Michael Salomon, Regina Ensenauer, Eva Reischl, Lena Hoerburger, Harald Grallert, Gabi Kastenmüller, Annette Peters, Hannelore Daniel, Jan Krumsiek, Fabian J. Theis, Hans Hauner, Helmut Laumen
PLoS One. 2019; 14(5): e0216110. Published online 2019 May 23. doi: 10.1371/journal.pone.0216110
PMCID:
PMC6532850
ArticlePubReaderPDF–959KCite
2.
TNF-α and IGF1 modify the microRNA signature in skeletal muscle cell differentiation
Swanhild U Meyer, Christian Thirion, Anna Polesskaya, Stefan Bauersachs, Sebastian Kaiser, Sabine Krause, Michael W Pfaffl
Cell Commun Signal. 2015; 13: 4. Published online 2015 Jan 29. doi: 10.1186/s12964-015-0083-0
PMCID:
PMC4325962
ArticlePubReaderPDF–1.0MCite
3.
A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment
Nataša Anastasov, Ines Höfig, Vanja Radulović, Simon Ströbel, Michael Salomon, Jan Lichtenberg, Ina Rothenaigner, Kamyar Hadian, Jens M. Kelm, Christian Thirion, Michael J. Atkinson
BMC Cancer. 2015; 15: 466. Published online 2015 Jun 10. doi: 10.1186/s12885-015-1481-9
PMCID:
PMC4460881
ArticlePubReaderPDF–1.3MCite
4.
Profound Effect of Profiling Platform and Normalization Strategy on Detection of Differentially Expressed MicroRNAs – A Comparative Study
Swanhild U. Meyer, Sebastian Kaiser, Carola Wagner, Christian Thirion, Michael W. Pfaffl
PLoS One. 2012; 7(6): e38946. Published online 2012 Jun 18. doi: 10.1371/journal.pone.0038946
PMCID:
PMC3377731
ArticlePubReaderPDF–789KCite
5.
Breaking Entry-and Species Barriers: LentiBOOST® Plus Polybrene Enhances Transduction Efficacy of Dendritic Cells and Monocytes by Adenovirus 5
Astrid Strack, Andrea Deinzer, Christian Thirion, Silke Schrödel, Jan Dörrie, Tatjana Sauerer, Alexander Steinkasserer, Ilka Knippertz
Viruses. 2022 Jan; 14(1): 92. Published online 2022 Jan 5. doi: 10.3390/v14010092
PMCID:
PMC8781300
ArticlePubReaderPDF–9.8MCite
6.
Osteogenic Differentiation of Human Adipose-Derived Stem Cells Seeded on a Biomimetic Spongiosa-like Scaffold: Bone Morphogenetic Protein-2 Delivery by Overexpressing Fascia
Bin Ren, Oliver B. Betz, Daniel Seitz, Christian Thirion, Michael Salomon, Volkmar Jansson, Peter E. Müller, Volker M. Betz
Int J Mol Sci. 2022 Mar; 23(5): 2712. Published online 2022 Feb 28. doi: 10.3390/ijms23052712
PMCID:
PMC8911081
ArticlePubReaderPDF–4.3MCite
7.
Design and Immunological Validation of Macaca fascicularis Papillomavirus Type 3 Based Vaccine Candidates in Outbred Mice: Basis for Future Testing of a Therapeutic Papillomavirus Vaccine in NHPs
Patrick Neckermann, Ditte Rahbaek Boilesen, Torsten Willert, Cordula Pertl, Silke Schrödel, Christian Thirion, Benedikt Asbach, Peter Johannes Holst, Ralf Wagner
Front Immunol. 2021; 12: 761214. Published online 2021 Oct 28. doi: 10.3389/fimmu.2021.761214
PMCID:
PMC8581358
ArticlePubReaderPDF–2.3MCite
8.
Gene activated adipose tissue fragments as advanced autologous biomaterials for bone regeneration: osteogenic differentiation within the tissue and implications for clinical translation
Bin Ren, Volker M. Betz, Christian Thirion, Michael Salomon, Roland M. Klar, Volkmar Jansson, Peter E. Müller, Oliver B. Betz
Sci Rep. 2019; 9: 224. Published online 2019 Jan 18. doi: 10.1038/s41598-018-36283-6
PMCID:
PMC6338750
ArticlePubReaderPDF–2.9MCite
9.
Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization
Dennis Lapuente, Jana Fuchs, Jonas Willar, Ana Vieira Antão, Valentina Eberlein, Nadja Uhlig, Leila Issmail, Anna Schmidt, Friederike Oltmanns, Antonia Sophia Peter, Sandra Mueller-Schmucker, Pascal Irrgang, Kirsten Fraedrich, Andrea Cara, Markus Hoffmann, Stefan Pöhlmann, Armin Ensser, Cordula Pertl, Torsten Willert, Christian Thirion, Thomas Grunwald, Klaus Überla, Matthias Tenbusch
Nat Commun. 2021; 12: 6871. Published online 2021 Nov 26. doi: 10.1038/s41467-021-27063-4
PMCID:
PMC8626513
ArticlePubReaderPDF–1.2MCite
10.
Adenovirus based virus-like-vaccines targeting endogenous retroviruses can eliminate growing colorectal cancers in mice
Lasse Neukirch, Tea Kirkegaard Nielsen, Henriette Laursen, Joana Daradoumis, Christian Thirion, Peter Johannes Holst
Oncotarget. 2019 Feb 15; 10(14): 1458–1472. Published online 2019 Feb 15. doi: 10.18632/oncotarget.26680
PMCID:
PMC6402721
ArticlePubReaderPDF–2.8MCite
11.
Vaccine vectors based on Adenovirus 19a/64 exhibit broad cellular tropism and potently restimulate HCMV-specific T cell responses ex vivo
Richard Kiener, Markus Fleischmann, Christiane Schwegler, Zsolt Ruzsics, Christian Thirion, Silke Schrödel, Benedikt Asbach, Ralf Wagner
Sci Rep. 2018; 8: 1474. Published online 2018 Jan 24. doi: 10.1038/s41598-018-19874-1
PMCID:
PMC5784015
ArticlePubReaderPDF–4.1MCite
12.
Generation of human fatty livers using custom-engineered induced pluripotent stem cells with modifiable SIRT1 metabolism
Alexandra Collin de l’Hortet, Kazuki Takeishi, Jorge Guzman-Lepe, Kazutoyo Morita, Abhinav Achreja, Branimir Popovic, Yang Wang, Kan Handa, Anjali Mittal, Noah Meurs, Ziwen Zhu, Frank Weinberg, Michael Salomon, Ira J Fox, Chu-Xia Deng, Deepak Nagrath, Alejandro Soto-Gutierrez
Cell Metab. Author manuscript; available in PMC 2020 Aug 6.
Published in final edited form as: Cell Metab. 2019 Aug 6; 30(2): 385–401.e9. doi: 10.1016/j.cmet.2019.06.017
PMCID:
PMC6691905
ArticlePubReaderPDF–3.9MCite
13.
Tumor Necrosis Factor Alpha and Insulin-Like Growth Factor 1 Induced Modifications of the Gene Expression Kinetics of Differentiating Skeletal Muscle Cells
Swanhild U. Meyer, Stefan Krebs, Christian Thirion, Helmut Blum, Sabine Krause, Michael W. Pfaffl
PLoS One. 2015; 10(10): e0139520. Published online 2015 Oct 8. doi: 10.1371/journal.pone.0139520
PMCID:
PMC4598026
ArticlePubReaderPDF–2.3MCite
14.
Integrative Analysis of MicroRNA and mRNA Data Reveals an Orchestrated Function of MicroRNAs in Skeletal Myocyte Differentiation in Response to TNF-α or IGF1
Swanhild U. Meyer, Steffen Sass, Nikola S. Mueller, Stefan Krebs, Stefan Bauersachs, Sebastian Kaiser, Helmut Blum, Christian Thirion, Sabine Krause, Fabian J. Theis, Michael W. Pfaffl
PLoS One. 2015; 10(8): e0135284. Published online 2015 Aug 13. doi: 10.1371/journal.pone.0135284
PMCID:
PMC4536022
ArticlePubReaderPDF–3.7MCite
15.
A new web-based method for automated analysis of muscle histology
Cordula Pertl, Markus Eblenkamp, Anja Pertl, Stefan Pfeifer, Erich Wintermantel, Hanns Lochmüller, Maggie C Walter, Sabine Krause, Christian Thirion
BMC Musculoskelet Disord. 2013; 14: 26. Published online 2013 Jan 16. doi: 10.1186/1471-2474-14-26
PMCID:
PMC3560198
ArticlePubReaderPDF–1.1MCite
16.
Inhibition of histone deacetylation rescues phenotype in a mouse model of Birk-Barel intellectual disability syndrome
Alexis Cooper, Tamer Butto, Niklas Hammer, Somanath Jagannath, Desiree Lucia Fend-Guella, Junaid Akhtar, Konstantin Radyushkin, Florian Lesage, Jennifer Winter, Susanne Strand, Jochen Roeper, Ulrich Zechner, Susann Schweiger
Nat Commun. 2020; 11: 480. Published online 2020 Jan 24. doi: 10.1038/s41467-019-13918-4
PMCID:
PMC6981138
ArticlePubReaderPDF–2.9MCite
17.
Arming T Cells with a gp100-Specific TCR and a CSPG4-Specific CAR Using Combined DNA- and RNA-Based Receptor Transfer
Bianca Simon, Dennis C. Harrer, Beatrice Schuler-Thurner, Gerold Schuler, Ugur Uslu
Cancers (Basel) 2019 May; 11(5): 696. Published online 2019 May 20. doi: 10.3390/cancers11050696
PMCID:
PMC6562862
ArticlePubReaderPDF–1.7MCite
18.
Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction
Baptiste Lamarthée, Armance Marchal, Soëli Charbonnier, Tifanie Blein, Juliette Leon, Emmanuel Martin, Lucas Rabaux, Katrin Vogt, Matthias Titeux, Marianne Delville, Hélène Vinçon, Emmanuelle Six, Nicolas Pallet, David Michonneau, Dany Anglicheau, Christophe Legendre, Jean-Luc Taupin, Ivan Nemazanyy, Birgit Sawitzki, Sylvain Latour, Marina Cavazzana, Isabelle André, Julien Zuber
Nat Commun. 2021; 12: 6446. Published online 2021 Nov 8. doi: 10.1038/s41467-021-26844-1
PMCID:
PMC8575891
ArticlePubReaderPDF–5.0MCite
19.
Optimizing Lentiviral Vector Transduction of Hematopoietic Stem Cells for Gene Therapy
Yoonjeong Jang, Yoon-Sang Kim, Matthew M. Wielgosz, Francesca Ferrara, Zhijun Ma, Jose Condori, Lance E. Palmer, Xiwen Zhao, Guolian Kang, David J. Rawlings, Sheng Zhou, Byoung Y. Ryu
Gene Ther. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Gene Ther. 2020 Dec; 27(12): 545–556. Published online 2020 Apr 27. doi: 10.1038/s41434-020-0150-z
PMCID:
PMC7606410
ArticlePubReaderPDF–753KCite
20.
A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem Cells
Marianne Delville, Tayebeh Soheili, Florence Bellier, Amandine Durand, Adeline Denis, Chantal Lagresle-Peyrou, Marina Cavazzana, Isabelle Andre-Schmutz, Emmanuelle Six
Mol Ther Methods Clin Dev. 2018 Sep 21; 10: 341–347. Published online 2018 Aug 8. doi: 10.1016/j.omtm.2018.08.002
PMCID:
PMC6125771
ArticlePubReaderPDF–1.1MCite

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