PMC

(A–D) The liver tissues histology (left) of tumor‐bearing mice from Control, Maitake Pro4X, Maitake Standard, and the normal liver from animals without breast tumor that resist carcinogenesis after treatment with Maitake Pro4X, respectively. Black arrows represent the cell proliferation area. Right pictures from each histology, represents the liver tissue in each condition. Red arrows represent the metastasis area.

Histology of mammary tissues from each treatment group with or without Maitake. The picture indicated as normal breast corresponded to breast tissues without tumor developed after Maitake Pro4X treatment. Right picture shows the paraffin block of breast tissues, the arrow indicate the amplified region and left picture shows the corresponding microscopy breast histology.

Representative BIC chromatogram for Reishi, Maitake and Lion’s Mane extracts.

Breast cancer prevention induces by Maitake. This figure indicates the average results obtained from three independent experiments. *P < 0.05, **P < 0.01.